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Article Abstract

Chimeric antigen receptor T (CAR T) cell therapy achieved remarkable success in B-cell leukemia and lymphoma which led to its incorporation in treatment protocols for these diseases. CAR T cell therapy for chronic lymphocytic leukemia (CLL) patients showed less success compared to other malignant tumors. In this review, we discuss the published results regarding CAR T cell therapy of CLL, possible mechanisms of failures and expected developments.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139644PMC
http://dx.doi.org/10.3390/curroncol29050293DOI Listing

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