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http://dx.doi.org/10.1002/cac2.12296 | DOI Listing |
Curr Med Chem
August 2024
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Background: Entrectinib, a ROS1 inhibitor, is effective in patients with ROS1-positive non-small-cell lung cancer (NSCLC). However, entrectinib resistance remains a challenge worldwide. The biomarkers of entrectinib resistance and molecular mechanisms have not been clarified based on the Gene Expression Omnibus (GEO) database.
View Article and Find Full Text PDFAging (Albany NY)
February 2024
School of Clinical Medicine, Guizhou Medical University, Guiyang, China.
Physiol Genomics
October 2023
School of Public Health, North China University of Science and Technology, Tangshan, People's Republic of China.
Lung squamous cell carcinoma (LUSC) is a non-small cell lung cancer with a poor prognosis owing to late diagnosis. New molecular markers are urgently needed to improve the diagnosis and prognosis of LUSC. 7-Methylguanosine (mG) modifications, a tRNA modification, are common in eubacteria, eukaryotes, and a few archaea.
View Article and Find Full Text PDFJ Gastrointest Oncol
June 2023
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Background: The incidence and mortality of pancreatic cancer are almost the same, and the 5-year survival rate is less than 10%. The high mortality of pancreatic cancer is related to chemo-radiotherapy. The present study aimed to establish a prognostic signature of pancreatic cancer based on chemo-radiotherapy resistant-related genes (CRRGs).
View Article and Find Full Text PDFOncogene
May 2023
Molecular Oncology, PSL Research University, CNRS, UMR 144, Institut Curie, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.
Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these distinct subtypes are regulated remains unclear.
View Article and Find Full Text PDF