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Neuraxial anaesthesia is an essential technique in obstetric anaesthesia practice. Cerebrospinal fluid (CSF) fistula is a rare complication and there is no consensus about its clinical approach. We present a case of a 28-year-old nulliparous woman that developed a cutaneous CSF fistula following combined spinal and epidural block for caesarean delivery. After multidisciplinary discussion it was decided that hydration, absolute bed-rest and compressive dressing with abdominal binder was the best option and the patient fully recovered without any sequelae.Based on literature, symptoms of intracranial hypotension and leakage of clear fluid surrounding the puncture site usually motivate referral to anaesthesia. Management strategies can be both conservative and invasive, including direct suture of the skin puncture site and epidural blood patch.Regarding the anaesthesia practice on this topic, most of the available evidence is based on case reports, rendering the decision-making process challenging.
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http://dx.doi.org/10.1136/bcr-2021-247598 | DOI Listing |
Aim: Hydrocephalus is a condition characterized by the excessive accumulation of cerebrospinal fluid in the brain's ventricular system, leading to ventricular enlargement and increased intracranial pressure. This study aimed to evaluate whether transfontanel ultrasonography could serve as a practical and less complex alternative to brain magnetic resonance imaging in infants with hydrocephalus.
Material And Methods: In this prospective study, 54 infants diagnosed with hydrocephalus underwent both transfontanel ultrasonography and brain magnetic resonance imaging.
ACS Sens
September 2025
Department of Pharmacy, The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences, Nanning, Guangxi 530021, China.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by cognitive decline and behavioral impairments, typically manifesting in the elderly and presenile population. With the rapid global aging trend, early diagnosis and treatment of AD have become increasingly urgent research priorities. The primary pathological features of AD include excessive accumulation of β-amyloid (Aβ) plaques, the formation of neurofibrillary tangles, and neuronal loss.
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September 2025
Department of Neurosurgery and the Training Base of Neuroendoscopic Physicians under the Chinese Medical Doctor Association, Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.
Background And Objectives: Microvascular decompression (MVD) for hemifacial spasm (HFS) is commonly conducted under a microscope. We report a large series of fully endoscopic MVDs for HFS and describe our initial experience with 3-dimensional (3D) endoscopy.
Methods: Clinical data of 204 patients with HFS who underwent fully endoscopic MVD using 2-dimensional (2D) and 3D endoscopy (191 and 13 patients, respectively) from July 2017 to October 2024 were retrospectively analyzed.
Biol Psychiatry Glob Open Sci
November 2025
Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
Background: Neuroimmune processes are often implicated in young people with atypical neuropsychiatric disorders, yet treatment implications remain controversial. This case series details young people with primary psychiatric disorders who received adjunctive immunotherapy after thorough investigation and extensive conventional treatments.
Methods: We evaluated 45 individuals (93% female, ages 12-30 years) with atypical psychiatric presentations suggesting potential neuroimmune involvement.
Front Vet Sci
August 2025
Fitzpatrick Referrals, Neurology Service, Eashing, United Kingdom.
Pug dogs are predisposed to thoracolumbar myelopathy associated with vertebral articular process dysplasia, suggesting a biomechanical etiology. While surgery is commonly pursued, long-term outcomes remain poorly defined. This retrospective descriptive case series reports on seven Pug dogs that underwent surgical treatment for thoracolumbar myelopathy and were followed up for at least 7 years postoperatively.
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