98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111652 | PMC |
http://dx.doi.org/10.1111/dth.15363 | DOI Listing |
Clin Cosmet Investig Dermatol
September 2025
Department of Dermatology, Wuhan Asia General Hospital, Wuhan Asia General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, 430000, People's Republic of China.
Background: Topical glucocorticoids are widely used in psoriasis treatment but may lead to systemic adverse effects, particularly with prolonged use. While pediatric cases are well-documented, adult-onset iatrogenic Cushing's syndrome from topical corticosteroids remains under-recognized.
Case Presentation: A 31-year-old woman with a 10-year history of psoriasis vulgaris self-administered high-potency clobetasol propionate ointment (monthly cumulative dose escalated from 30 g to 100 g over 22 months) under no physician supervision.
Inflamm Res
June 2025
Department of Dermatology, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Shanghai, China.
Background: Erythrodermic pemphigus foliaceus (EPF) is a severe, often refractory autoimmune disease.
Method: We report successful treatment of refractory EPF in a 59-year-old male using low-dose rituximab (RTX) and intravenous immunoglobulin (IVIG).
Results: Initial high-dose corticosteroids and IVIG failed, complicated by infections.
J Dermatol Sci
April 2025
Dermatology Hospital, Southern Medical University, Guangzhou, China. Electronic address:
Background: Progressive symmetric erythrokeratodermia (PSEK) is a group of hereditary cornification disorders characterized by symmetrical, progressive erythroderma and hyperkeratosis over the body. Loss-of-function variants in SLURP1, encoding secreted Ly-6/uPAR-related protein 1, is known to cause Mal de Meleda, an autosomal recessive palmoplantar keratoderma.
Objective: To identify the genetic basis and the pathogenesis of a sporadic patient with PSEK.
Cureus
September 2024
Dermatology, Imperial Dermatology, Hollywood, USA.