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Wound closure with surgical sutures is a critical challenge for flexible endoscopic surgeries. Substantial efforts have been introduced to develop functional and smart surgical sutures to either monitor wound conditions or ease the complexity of knot tying. Although research interests in smart sutures by soft robotic technologies have emerged for years, it is challenging to develop a soft robotic structure that possesses a similar physical structure as conventional sutures while offering a self-tightening knot or anchor to close the wound. This paper introduces a new concept of smart sutures that can be programmed to achieve desired and uniform tension distribution while offering self-tightening knots or automatically deploying secured anchors. The core technology is a soft hydraulic artificial muscle that can be elongated and contracted under applied fluid pressure. Each suture is equipped with a pressure locking mechanism to hold its temporary elongated state and to induce self-shrinking ability. The puncturing and holding force for the smart sutures with anchors are examined. Ex-vivo experiments on fresh porcine stomach and colon demonstrate the usefulness of the new smart sutures. The new approaches are expected to pave the way for the further development of smart sutures that will benefit research, training, and commercialization in the surgical field.
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http://dx.doi.org/10.1038/s41598-021-01910-2 | DOI Listing |
J Gastrointest Surg
August 2025
Division of Digestive Surgery (Esophageal and Gastric Surgery Division), Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kawaramachi-hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Background: Lower mediastinal esophagogastrostomy after proximal gastrectomy with lower esophagectomy for esophagogastric junction (EGJ) cancer remains technically demanding due to the high risk of anastomotic leakage and reflux. We developed a novel reconstruction technique, the short middle overlap anastomosis reinforced with Toupet-like fundoplication (SMART) method, to address these challenges.
Methods: From March 2017 to April 2025, 40 patients underwent radical surgery for EGJ cancer at our institution.
Colloids Surf B Biointerfaces
August 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China. Electronic address:
Multifunctional medical sutures (MMSs), constructed through the integration of biomaterials, drug-delivery systems, and advanced surface engineering, hold great promise for addressing surgical site infections (SSIs) and promoting tissue repair. Despite the increasing research interest, the fundamental relationship between MMSs design parameters and clinical performance remains insufficiently elucidated, which has hindered progress toward their clinical translation. This review offers a comprehensive analysis of the critical performance metrics of MMSs and elucidates the underlying correlations between their structural design and functional deployment to inform practical development strategies.
View Article and Find Full Text PDFAdv Mater
July 2025
The Laboratory for Advanced Functional/Medicinal Polymers & Smart Drug Delivery Technologies, The Wolfson Faculty of Chemical Engineering, Technion-Israel Institute of Technology, Haifa, 3200003, Israel.
Conventional suturing and stapling cause additional trauma, pain, and cost for patients. As alternatives, existing bioadhesives suffer from imprecise fabrication, limited wet tissue adhesion, and insufficient biological functionalities for effective wound management. This work proposes biomimetic hydrogel bioadhesives composed of modified natural tannic acid (TA), hyperbranched polylysine (HPL), and acrylic acid (AA), abbreviated PTLAs, to offer solutions for tissue adhesion under challenging environments (underwater, body fluids, cold, pressure), and for enhanced healthcare.
View Article and Find Full Text PDFSurg Endosc
August 2025
Department of Obstetrics and Gynaecology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.
Background: Robotic surgical systems have transformed modern medicine by enabling minimally invasive procedures with enhanced precision. However, current end-effector technologies face significant limitations in force feedback accuracy, environmental adaptability, and autonomous capabilities, necessitating innovative solutions to advance surgical robotics.
Methods: This comprehensive review evaluates existing end-effector technologies and emerging innovations through analysis of recent research developments.
J Mater Chem B
July 2025
Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Key Laboratory of Innovation and Transformation of Advanced Medical Devices, Ministry of Industry and Information Technology, National Medical Innovation Platform for Industry-Education Integration in Adva
Wound is the breakage of the skin caused by external damage, and it greatly enhances the risk of infection. Severe chronic wounds can typically lead to the deterioration of the wound condition, prolonged wound healing, complex medical treatment and even mortality. As a reliable strategy, diverse innovative medical dressings have demonstrated significant potential in accelerating wound healing.
View Article and Find Full Text PDF