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The aim of this study was to analyse the structural characteristics of the temporo-mandibular joint (TMJ) and the dysfunctional consequences induced by disease in subjects with juvenile idiopathic arthritis (JIA). The study was conducted in 25 patients with JIA (median age (IQR), 13.9 (10.9-15.3)) and 26 healthy controls (median age (IQR), 14.3 (11.6-17.2)) years. All enrolled patients were subjected to anamnestic evaluation, laboratory parameters, JIA subclass, and type of therapy for the disease. A clinical-gnathological evaluation, anamnestic and dysfunctional index (Ai and Di), and magnetic resonance imaging of TMJs were performed in all patients. The test group showed a significant reduction ( < 0.001) regarding the clinical findings such as maximal mouth opening, left and rightward laterotrusion and protrusion, and a significant difference in the reported symptoms (TMJ sounds, reduced mouth opening and pain), and Ai and Di ( < 0.001) compared to healthy patients. Correlation analysis showed a significant correlation between the median duration of disease and the maximum mouth opening and between visual analogue scale (VAS) score and maximum mouth opening, leftward laterotrusion, rightward laterotrusion, and protrusion. The results obtained in this study suggest that patients with JIA presented a cohort of symptoms in TMJs in comparison with healthy controls. Moreover, a careful TMJs evaluation and an early diagnosis of TMJs dysfunction and regular follow-ups are recommended in order to prevent and reduce functional and chewing problems in patients with JIA.
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http://dx.doi.org/10.3390/healthcare9091140 | DOI Listing |
Medicine (Baltimore)
September 2025
Department of Prosthodontics, Faculty of Dentistry, Van Lang University, Ho Chi Minh City, Vietnam.
This study examines the symptomatic and clinical features and variations in characteristics, such as angle and length of the condylar path in the sagittal plane during protrusion movement, in internal derangement patients treated with exercise therapy. Patients were selected and classified using the diagnostic criteria for temporomandibular disorders (DC/TMD) axis I. The therapeutic exercise program consisted of lateral jaw movements performed daily, with gradual progression to a target of 50 repetitions per day.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Animal Genetics, University of Tuebingen, 72076 Tuebingen, Germany.
Background: Membrane transport proteins are critical determinants of systemic and intracellular drug levels, thereby contributing substantially to drug response and/or adverse drug reactions. Therefore, the U.S.
View Article and Find Full Text PDFClin Exp Dent Res
October 2025
Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Objectives: Among the minimally invasive techniques for treating temporomandibular joint disorders (TMDs) is dry needling, which can be used as a potential treatment method. This study aims to review current knowledge to understand the impact of dry needling on treating TMDs.
Methods: This systematic review was carried out in alignment with the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).
Oral Dis
September 2025
Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, Brazil.
Objective: This study systematically reviewed the effect of intra-articular injection (IAI) of platelet-rich fibrin (i-PRF), alone or combined with arthrocentesis or arthroscopy, in managing painful articular temporomandibular disorders (TMD) and improving maximum mouth opening (MMO).
Materials And Methods: A systematic literature search was conducted in five databases, identifying randomized and nonrandomized clinical trials focusing on minimally invasive TMJ interventions using i-PRF. Meta-analyses were performed with a random-effects model for studies reporting similar outcomes, visual analog scale (VAS) scores for pain, and MMO values.
Strabismus
September 2025
Department of Ophthalmology, Barcelona Hospital, Barcelona University, Barcelona, Spain.
: We report a case of an unusual association between Duane retraction syndrome and Marcus Gunn jaw-winking syndrome in the eye of a patient without other anomalies.: Clinical case. A four-year-old boy presented mild blepharoptosis of the left upper eyelid.
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