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Purpose: The relationship between height and incident atrial fibrillation (AF) has recently been demonstrated. We aimed to evaluate the impact of height on outcomes of ablation in patients with drug-refractory symptomatic paroxysmal AF (PAF).
Methods: A total of 689 patients (470 males; age, 53.0 ± 11.7 years) with symptomatic paroxysmal AF receiving index catheter ablation (CA) between 2003 and 2013 were enrolled in this study. The baseline characteristics, ablation, and follow-up results were evaluated. The patients were categorized according to the quartiles of height for each sex.
Results: Patients in the lower quartiles of height had a lower incidence of AF recurrence (log-rank p = 0.022). Height in female patients was strongly associated with AF recurrence (p = 0.027) after an index ablation in the 6.33 ± 4.32 years of follow-up. Female patients > 159 cm in height had a higher likelihood of AF recurrence after index CA (HR = 2.01, 95% CI: 1.24-3.25, p = 0.005) than that in those below this height. In computed tomography (CT) scan, the superoinferior diameter of the left atrium (LA) correlated with body height in females, but not in male patients.
Conclusions: Height is associated with AF recurrence after the index CA of PAF in female patients. In Asian populations, women above height 159 cm are twice as likely to have AF recurrence post-ablation as shorter women.
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http://dx.doi.org/10.1007/s10840-021-01055-2 | DOI Listing |
Menopause
September 2025
Epidemiology Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Objective: The objective of the present work is to: (1) describe the trends in obesity among premenopausal and postmenopausal women in the United States between 1999 and 2018, and (2) describe the effect of aging on body mass index in women, using novel BMI-for-age percentile curves.
Methods: Data from the National Health and Nutrition Examination Survey (NHANES) collected between 1999 and 2018, including self-identified female participants older than 20 years, was used. Menopause status was self-reported, and body mass index (BMI, kg/m2) was calculated based on measured height and weight.
Cancer Immunol Res
September 2025
QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.
Natural killer (NK) cell licensing is an educational process that enhances responsiveness to activating signals in maturing NK cells and is predominantly regulated by major histocompatibility complex (MHC) class I-specific inhibitory signals. However, the role of non-MHC signalling in this process remains unclear. Here, we investigated the role of FcRγ, an adaptor protein associated with activating receptors, in the regulation of NK cell responsiveness.
View Article and Find Full Text PDFPLoS One
September 2025
Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Background: Metabolic syndrome (MetS) and sarcopenia are major global public health problems, and their coexistence significantly increases the risk of death. In recent years, this trend has become increasingly prominent in younger populations, posing a major public health challenge. Numerous studies have regarded reduced muscle mass as a reliable indicator for identifying pre-sarcopenia.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Department of Orthopaedics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Introduction: Pediatric endotracheal intubation is challenging due to airway anatomical differences. Accurate endotracheal tube (ETT) sizing is crucial for effective ventilation and preventing complications. Traditional age, weight, or height-based methods are often unreliable, leading to multiple attempts.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.