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Developing and Validating a Multi-Domain Risk Attitudes Scale in the Multi-Ethnic Asian Population in Singapore.
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Maladaptive risk attitudes, such as extreme risk seeking and risk aversion, are closely linked to psychopathology such as psychopathy and anxiety. Having culturally appropriate assessments of risk attitudes is essential for the research of psychology and psychopathology of responses to risk in a target population. We aimed to develop and validate the multi-domain risk tolerance (MDRT) scale for the multi-ethnic Singaporean population.
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Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
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