Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255063 | PMC |
| http://dx.doi.org/10.1002/ctm2.476 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Gradient hydrogel with bioactive glass for tendon-bone interface regeneration: Enhancing biomechanical strength and synchronized tissue regeneration.
Acta Biomater
August 2025
Shanghai Frontiers Science Center of Advanced Textiles, College of Textiles, Donghua University, Shanghai 201620, China; Key Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China. Electronic address:
The interface between tendon and bone is characterized by a gradient multi-tissue structure in a small-sized, localized region, and the tendon insertion cannot fully regenerate following repair for its rupture. Therefore, tendon-bone healing remains a significant challenge in the field of sports medicine. This study aims to design and fabricate a bioactive hydrogel with a continuous ion concentration gradient, using bioactive glass (BG), modified alginate (AlgMA), and gelatin.
View Article and Find Full Text PDFHarnessing cell size to separate genetically and functionally distinct dental pulp-derived mesenchymal stromal cell subpopulations.
J Biol Eng
June 2025
Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Disease, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330209, China.
Background: Dental pulp-derived mesenchymal stromal cells (DPMSCs) represent a promising avenue for regenerative medicine. However, the therapeutic potency of DPMSCs is substantially influenced by their functional heterogeneity emerging during ex vivo expansion. Therefore, identifying and selecting the most potent subpopulation of DPMSCs following expansion is key to improving therapeutic efficacy and consistency.
View Article and Find Full Text PDFConstruction and high-throughput screening of gradient nanowire coatings on titanium surface towards ameliorated osseointegration.
Mater Today Bio
February 2025
Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Surface nano-modification has emerged as an effective strategy to enhance osseointegration of titanium (Ti) implants. Despite its promise, rational optimization of surface nanomorphology for ameliorated osseointegration remains a significant challenge. Our research pioneering developed a one-step alkali etching technique to produce a gradient nanowire coating with continuously varied dimensions on Ti surfaces, which was subsequently served as a versatile platform for high-throughput screening of optimal dimensions to enhance osseointegration.
View Article and Find Full Text PDFEfficient Treatment of Psoriasis Using Conditioned Media from Mesenchymal Stem Cell Spheroids Cultured to Produce Transforming Growth Factor-1-Enriched Small-Sized Extracellular Vesicles.
Int J Stem Cells
November 2024
Department of Stem Cell and Regenerative Biotechnology, Molecular & Cellular Reprogramming Center and Institute of Advanced Regenerative Science, Konkuk University, Seoul, Korea.
Psoriasis is a common chronic inflammatory disease in which keratinocytes proliferate abnormally due to excessive immune action. Psoriasis can be associated with various comorbidities and has a significant impact on health-related quality of life. Although many systemic treatments, including biologic agents, have been developed, topical treatment remains the main option for psoriasis management.
View Article and Find Full Text PDFTracking epithelial-mesenchymal transition in breast cancer cells based on a multiplex electrochemical immunosensor.
Biosens Bioelectron
August 2024
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.
Epithelial-mesenchymal transition (EMT) promotes tumor cell infiltration and metastasis. Tracking the progression of EMT could potentially indicate early cancer metastasis. A key characteristic of EMT is the dynamic alteration in the molecular levels of E-cadherin and N-cadherin.
View Article and Find Full Text PDF