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Seismic surveys are used to locate oil and gas reserves below the seabed and can be a major source of noise in marine environments. Their effects on commercial fisheries are a subject of debate, with experimental studies often producing results that are difficult to interpret. We overcame these issues in a large-scale experiment that quantified the impacts of exposure to a commercial seismic source on an assemblage of tropical demersal fishes targeted by commercial fisheries on the North West Shelf of Western Australia. We show that there were no short-term (days) or long-term (months) effects of exposure on the composition, abundance, size structure, behavior, or movement of this fauna. These multiple lines of evidence suggest that seismic surveys have little impact on demersal fishes in this environment.
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http://dx.doi.org/10.1073/pnas.2100869118 | DOI Listing |
IEEE Trans Neural Netw Learn Syst
September 2025
Knowledge distillation (KD) aims to transfer knowledge from a large-scale teacher model to a lightweight one, significantly reducing computational and storage requirements. However, the inherent learning capacity gap between the teacher and student often hinders the sufficient transfer of knowledge, motivating numerous studies to address this challenge. Inspired by the progressive approximation principle in the Stone-Weierstrass theorem, we propose expandable residual approximation (ERA), a novel KD method that decomposes the approximation of residual knowledge into multiple steps, reducing the difficulty of mimicking the teacher's representation through a divide-and-conquer approach.
View Article and Find Full Text PDFHum Reprod Open
August 2025
Department of Molecular Cell Biology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Vilnius, Lithuania.
Study Question: What is the effect of hCG on the epigenetic profile and the expression of other molecular factors in endometrial stromal cells (ESCs)?
Summary Answer: Our findings suggest that hCG treatment alters the molecular environment of decidualized ESCs, potentially influencing implantation and immune regulation through epigenetic modifications and changes in the levels of secreted proteins and micro-ribonucleic acids (miRNAs).
What Is Known Already: Embryo implantation depends not only on the quality of the embryo but also on the receptivity of the endometrium, the specialized lining of the uterus that undergoes dynamic changes to support pregnancy. Effective communication between the maternal and fetal compartments, facilitated by molecular signals and cellular interactions, is essential for successful implantation.
Int J Nanomedicine
September 2025
College of Basic Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, People's Republic of China.
Purpose: Natural killer (NK) cell-derived extracellular vesicles (NK-EVs) have garnered significant research interest in the field of tumor immunotherapy. However, the large-scale production of NK-EVs remains a major challenge, limiting their clinical application. This study aims to develop a simple and efficient method for the preparation of NK cell-derived nanovesicles (NK-NVs) and to evaluate their cytotoxicity and drug delivery potential.
View Article and Find Full Text PDFStat Biosci
August 2024
Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Large-scale genomics data combined with Electronic Health Records (EHRs) illuminate the path towards personalized disease management and enhanced medical interventions. However, the absence of "gold standard" disease labels makes the development of machine learning models a challenging task. Additionally, imbalances in demographic representation within datasets compromise the development of unbiased healthcare solutions.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
School of Artificial Intelligence, Jilin University, Changchun, 130012, China.
Single-cell multi-omics technologies are pivotal for deciphering the complexities of biological systems, with Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) emerging as a particularly valuable approach. The dual-modality capability makes CITE-seq particularly advantageous for dissecting cellular heterogeneity and understanding the dynamic interplay between transcriptomic and proteomic landscapes. However, existing computational models for integrating these two modalities often struggle to capture the complex, non-linear interactions between RNA and antibody-derived tags (ADTs), and are computationally intensive.
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