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http://dx.doi.org/10.1097/CM9.0000000000001414 | DOI Listing |
Nanomicro Lett
September 2025
College of New Materials and New Energies, Shenzhen Technology University, Lantian Road 3002, Pingshan, 518118, Shenzhen, People's Republic of China.
The introduction of two-dimensional (2D) perovskite layers on top of three-dimensional (3D) perovskite films enhances the performance and stability of perovskite solar cells (PSCs). However, the electronic effect of the spacer cation and the quality of the 2D capping layer are critical factors in achieving the required results. In this study, we compared two fluorinated salts: 4-(trifluoromethyl) benzamidine hydrochloride (4TF-BA·HCl) and 4-fluorobenzamidine hydrochloride (4F-BA·HCl) to engineer the 3D/2D perovskite films.
View Article and Find Full Text PDFBiomater Sci
September 2025
Biotechnology Science and Engineering Program, University of Alabama in Huntsville, Huntsville, AL 35899, USA.
B cells are critical components of the adaptive immune system that proliferate and differentiate within the secondary lymphoid organs upon recognition of antigens and engagement of T cells. Traditional two-dimensional (2D) cell cultures fall short of replicating the intricate structures and dynamic evolution of three-dimensional (3D) environments found in lymphoid organs, prompting the development of more physiologically pertinent models. Our approach employs -hexanoyl glycol chitosan (HGC) coated ultra-low attachment (ULA) lattice plates to cultivate a 3D co-culture of CD40L-expressing MS5 stromal cells and naïve B cells derived from the peripheral blood mononuclear cells (PBMCs) of healthy human donors.
View Article and Find Full Text PDFAdv Pharm Bull
July 2025
Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Purpose: The survival and progression of multiple myeloma (MM) cells rely heavily on supportive factors and cells within the MM microenvironment, notably macrophages. The PI3K signaling pathway plays a crucial role in both myeloma cells survival and macrophage polarity, making it a potential target for altering the MM microenvironment dynamics.
Methods: In this study, the impact of LY294002, a PI3K signaling pathway inhibitor, on the viability of U266 myeloma cells in mono-culture and MM patient-derived bone marrow mononuclear cells (BM-MNCs) in co-culture was investigated.
J Ultrasound Med
September 2025
Department of Ultrasound, Donghai Hospital Affiliated to Kangda College of Nanjing Medical University, Lianyungang, China.
Objective: The aim of this study is to evaluate the prognostic performance of a nomogram integrating clinical parameters with deep learning radiomics (DLRN) features derived from ultrasound and multi-sequence magnetic resonance imaging (MRI) for predicting survival, recurrence, and metastasis in patients diagnosed with triple-negative breast cancer (TNBC) undergoing neoadjuvant chemotherapy (NAC).
Methods: This retrospective, multicenter study included 103 patients with histopathologically confirmed TNBC across four institutions. The training group comprised 72 cases from the First People's Hospital of Lianyungang, while the validation group included 31 cases from three external centers.
Acta Crystallogr E Crystallogr Commun
September 2025
Department of Chemistry, University of Gondar, PO Box 196, Gondar, Ethiopia.
The conformation of the title mol-ecule, CHClNO, is maintained by intra-molecular N-H⋯O, C-H⋯O, and C-H⋯Cl inter-actions, creating (6), (5), and (6) motifs, respectively. In the crystal, inter-molecular N-H⋯O, C-H⋯O, and C-H⋯Cl inter-actions connect the mol-ecules, forming a three-dimensional network. Additionally, the mol-ecules are linked by C-H⋯π inter-actions, forming layers parallel to the (002) plane.
View Article and Find Full Text PDF