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http://dx.doi.org/10.1097/CM9.0000000000001196 | DOI Listing |
Insect Sci
September 2025
Hubei Key Laboratory of Resources Utilization and Sustainable Pest Management, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China.
Phototaxis is a critical behavior in insects and is closely linked to vision and environmental adaptation. Understanding how insects perceive light and exhibit phototactic responses is crucial for assessing the ecological impact of artificial light at night. However, the molecular and neural mechanisms that regulate phototactic responses in insects remain largely unknown.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, P.R. China.
Developing artificial hosts with temperature-driven conformational switching behaviors facilitates our understanding of the temperature-dependent allostery and adaptation mechanisms in natural recognition systems. Herein, we report the design and synthesis of three pairs of water-soluble, enantiomeric binaphthalene-based tetraimidazolium macrocycles (SS/RR-1•4Cl- - SS/RR-3•4Cl-) as artificial hosts for exploring sequence-selective recognition of dinucleotides in aqueous media. Owing to the reversible rotational conformation of axially chiral binaphthyl units, SS-1•4Cl- demonstrates the conformational switching, converting from cis-conformation (SS-1) to trans-conformation (SS-1) by increasing temperature, thereby causing the recognition cavity to transition from a closed to an open state.
View Article and Find Full Text PDFBrain Behav
September 2025
The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Background: Diverse correlations between structural brain abnormalities and the clinical feature of bulimia nervosa (BN) have been identified in previous observational studies.
Objective: To explore the bidirectional causality between BN and brain structural magnetic resonance imaging (MRI) phenotypes.
Methods: Genome-wide association studies (GWAS) of 2441 participants identified genetic variants associated with disordered eating and predicted BN, whereas UK Biobank 3D-T1 MRI data were used to analyze brain structural phenotypes.
Genome Biol
September 2025
Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang, Hangzhou, 310029, China.
Metagenomic analyses of microbial communities have unveiled a substantial level of interspecies and intraspecies genetic diversity by reconstructing metagenome-assembled genomes (MAGs). The MAG database (MAGdb) boasts an impressive collection of 74 representative research papers, spanning clinical, environmental, and animal categories and comprising 13,702 paired-end run accessions of metagenomic sequencing and 99,672 high quality MAGs with manually curated metadata. MAGdb provides a user-friendly interface that users can browse, search, and download MAGs and their corresponding metadata information.
View Article and Find Full Text PDFAnal Bioanal Chem
September 2025
School of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, 310018, China.
The prompt and accurate identification of pathogenic bacteria is crucial for mitigating the transmission of infections. Conventional detection methods face limitations, including lengthy processing, complex sample pretreatment, high instrumentation costs, and insufficient sensitivity for rapid on-site screening. To address these challenges, an aptamer (Apt)-sensor based on functionalized magnetic nanoparticles (MNPs) was developed for detecting Escherichia coli.
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