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Most children with ADHD have impaired working memory abilities. These working memory deficits predict impairments in activities of daily living (ADLs) for adults with ADHD. However, our understanding of the relation between pediatric ADHD and ADLs is limited. Thus, this study aimed to examine (1) the extent to which pediatric ADHD is associated with ADL difficulties; and if so (2) the extent to which these difficulties are related to their well-documented working memory difficulties and/or core ADHD inattentive and hyperactive/impulsive symptom domains. A well-characterized, clinically evaluated sample of 141 children ages 8-13 years ( = 10.36, = 1.46; 51 girls; 70% White/non-Hispanic) were administered a battery of well-validated working memory tests and assessed for ADHD symptoms (teacher-ratings) and ADL difficulties (parent-ratings); cross-informant reports were used to control for mono-informant bias. Children with ADHD exhibited medium magnitude difficulties with ADLs ( = 0.61, p < .005, 38% impaired). Results of the bias-corrected, bootstrapped conditional effects model indicated that lower working memory predicted reduced performance of age-expected ADLs (=0.28) and greater ADHD inattentive (= -0.40) and hyperactive/impulsive symptoms (= -0.16). Greater inattentive, but not hyperactive/impulsive, symptoms predicted greater ADL difficulties (= -0.36) even after controlling for working memory. Interestingly, working memory exerted a significant indirect effect on ADLs via inattentive (indirect effect: = 0.15, effect ratio = .54) but not hyperactive/impulsive symptoms. These findings implicate ADHD inattentive symptoms as a potential mechanism underlying ADL difficulties for children with ADHD, both independently and via working memory's role in regulating attention.
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http://dx.doi.org/10.1080/09297049.2020.1866521 | DOI Listing |
Med Teach
September 2025
NordSim, Center for Skills Training and Simulation, Aalborg University Hospital, Aalborg, Denmark.
Background: Assessing skills in simulated settings is resource-intensive and lacks validated metrics. Advances in AI offer the potential for automated competence assessment, addressing these limitations. This study aimed to develop and validate a machine learning AI model for automated evaluation during simulation-based thyroid ultrasound (US) training.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan, China.
Many traditional classification networks directly use the limb two-lead signal (MLII) ECG signals as input for training. However, this method suffers from reduced accuracy when ECG features are not obvious, especially for premature heartbeats. To solve the issue, this paper proposed a novel network, namely CDLR-Net, that combines a Deep Residual Shrinkage Network (DRSN) with a Long Short-Term Memory (LSTM).
View Article and Find Full Text PDFBiol Psychol
September 2025
Institute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, 610066, China. Electronic address:
Working memory (WM) regulates information flow through gate mechanisms, consisting of four subprocesses: gate opening, gate closing, updating, and substitution. However, their neural mechanisms remain underexplored. While emotion-cognition interactions are well studied, the effects of negative mood on these subprocesses are unclear.
View Article and Find Full Text PDFAnal Biochem
September 2025
School of Computer Science and Engineering, Southeast University, Nanjing 210000, China.
In the complex process of gene expression and regulation, RNA-binding proteins occupy a pivotal position for RNA. Accurate prediction of RNA-protein binding sites can help researchers better understand RNA-binding proteins and their related mechanisms. And prediction techniques based on machine learning algorithms are both cost-effective and efficient in identifying these binding sites.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
Department of Psychology, Chung-Shan Medical University, Taichung, Taiwan; Clinical Psychological Room, Chung-Shan Medical University Hospital, Taichung, Taiwan. Electronic address:
Background: Previous research indicates near transfer effects of working memory (WM) training on updating, shifting, and inhibition tasks, although findings vary. Regarding fluid intelligence (Gf), studies yield conflicting results on the far transfer effects of WM training. The current study investigates whether different styles of adaptive visuospatial N-back WM training produce near and far transfer effects and whether individual differences moderate these effects.
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