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This study aimed to investigate different methods of obtaining high-quality Computed Tomography pulmonary angiography (CTPA) images using low-dose scanning in patients with different body mass index (BMI) values. Sixty patients with suspected pulmonary embolism were grouped based on their BMI values (BMI < 25, designated N, and BMI ≥ 25, designated O) and were assigned to receive either test bolus (TB) or bolus tracking (BT) at conventional (C) or low (L) dose. The effective dose (ED) in the N-TB-L group was lower than in the group N-TB-C (0.56 ± 0.05 vs. 3.78 ± 1.16, p < 0.001), with similar image quality (4.90 ± 0.31 vs. 4.70 ± 0.47, p = 0.120). The ED in the O-TB-L group was lower than in the O-TB-C group (0.54 ± 0.03 vs. 5.14 ± 1.34, p < 0.001), but the group O-TB-C's image quality was higher (4.65 ± 0.59 vs. 3.95 ± 0.89, p = 0.006). Groups N-TB-L versus O-TB-L, groups N-TB-L versus N-BT-L and groups O-TB-C versus O-BT-C had similar EDs (all ps > 0.05), but the image quality was different (all ps < 0.05). In conclusion, the results showed that the image quality of low-dose CTPA scanning using TB was similar to that of the conventional-dose CTPA in patients with BMI < 25 but was lower in patients with BMI ≥ 25. TB was better than BT for all patients, regardless of BMI, when receiving the same ED.
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http://dx.doi.org/10.1093/rpd/ncaa217 | DOI Listing |
Prog Nucl Magn Reson Spectrosc
September 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom; School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile; Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile; Institute for Biological and Medical
Cardiovascular magnetic resonance (CMR) imaging is an established non-invasive tool for the assessment of cardiovascular diseases, which are the leading cause of death globally. CMR provides dynamic and static multi-contrast and multi-parametric images, including cine for functional evaluation, contrast-enhanced imaging and parametric mapping for tissue characterization, and MR angiography for the assessment of the aortic, coronary and pulmonary circulation. However, clinical CMR imaging sequences still have some limitations such as the requirement for multiple breath-holds, incomplete spatial coverage, complex planning and acquisition, low scan efficiency and long scan times.
View Article and Find Full Text PDFJACC Case Rep
September 2025
Cardiovascular Imaging Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Among the many variations of total anomalous pulmonary venous connection, the one with dual drainage is extremely rare. This case series presents 3 patients with diverse variations in dual drainage total anomalous pulmonary venous connection thoroughly characterized by cardiac computed tomography angiography.
View Article and Find Full Text PDFAnn Vasc Surg
September 2025
Department of Oncology, Anhui Medical University Clinical College of Chest &Anhui Chest Hospital, Hefei, 230022, People's Republic of China.
Objective: This study aimed to characterize the association between pulmonary embolism (PE) onset and various anti-tumor therapeutic approaches in patients with lung cancer, with the goal of identifying potential high-risk populations.
Methods: A retrospective analysis was conducted on clinical records from 2019 to 2025, among the 84,000 inpatients with lung cancer, 106 patients developed PE during hospitalization for anti-tumor treatment, who were confirmed using spiral computed tomography (CT) or pulmonary angiography per CTS (2018) and NEJM (2010) criteria. Data were collected on patient demographics, cancer staging, treatment type, and time to PE onset.
Br J Radiol
September 2025
Division of Cardiovascular Medicine, University of Sheffield.
Objective: Characterisation of thrombus is important for guiding treatment in chronic thromboembolic pulmonary hypertension (CTEPH). This study presents a novel scoring system for visual assessment of CTEPH on CT pulmonary angiography (CTPA), incorporating both disease location and extent to determine the impact on survival outcomes.
Methods: Patients with CTEPH were identified retrospectively from the ASPIRE registry.
Eur Heart J Case Rep
September 2025
Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go A. Gemelli 1, Rome 00168, Italy.
Background: Chest pain is a common reason for emergency department (ED) visits, yet not all cases are attributable to coronary artery disease (CAD). The 2024 European Society of Cardiology (ESC) guidelines emphasize the importance of invasive coronary function testing in patients with angina and non-obstructive coronary arteries. Understanding alternative causes of chest pain is crucial for appropriate diagnosis and management.
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