Development and applications of artificial symmetrical proteins.

Comput Struct Biotechnol J

Laboratory of Biomolecular Modelling and Design, Department of Chemistry, KU Leuven, Celestijnenlaan 200G, 3001 Leuven, Belgium.

Published: November 2020


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Article Abstract

Since the determination of the first molecular models of proteins there has been interest in creating proteins artificially, but such methods have only become widely successful in the last decade. Gradual improvements over a long period of time have now yielded numerous examples of non-natural proteins, many of which are built from repeated elements. In this review we discuss the design of such symmetrical proteins and their various applications in chemistry and medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734218PMC
http://dx.doi.org/10.1016/j.csbj.2020.10.040DOI Listing

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