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Article Abstract
has been traditionally used to treat dysentery, enteritis, flatulence, and itchiness. However, the existence of anti-inflammatory effects of on -induced skin disease is unknown. In vitro cultures of plant cells and tissues produced under controlled conditions offer a continuous production platform for plant natural products including pigments and anti-inflammatory agents. In this study, we determine the anti-inflammatory activities of an extract of in vitro grown adventitious shoots of on , the etiologic agent of skin inflammation. The extract of showed antioxidant and anti-inflammatory activity in LPS-treated RAW264.7 cells. It also had antibacterial activity and anti-inflammatory effects on -treated HaCaT cells. In addition, these effects were regulated by suppression of the mitogen-activated protein kinase (MAPK) pathways. These results suggesting the potential application of adventitious shoots of grown with an in vitro proliferation system as a medicine for treating -induced inflammatory skin disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761664 | PMC |
| http://dx.doi.org/10.3390/plants9121701 | DOI Listing |
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