Comparative assessment of composting methods for the organic fraction of municipal solid waste: physicochemical insights.

Changes in consumption patterns, urbanization, and industrialization have led to the generation of large volumes of municipal solid waste (MSW), posing threats to environmental sustainability. This study aimed to compost the organic fraction of municipal solid waste (OFMSW) using three composting methods: windrow (WC), pit (PC), and drum composting (DC). Distilled water was used in compost preparation and sample analysis.

Transforming work in the digital era: AI-enhanced leadership and its effect on IT professional burnout.

This study examines the impact of AI-enhanced transformational leadership on IT professional burnout among Chinese IT professionals while investigating the mediating role of AI learning self-efficacy and the moderating effects of AI-enabled work practices and organizational AI-communication adequacy. Drawing on the technology-organization-environment (TOE) Framework, our research integrates traditional transformational leadership with emerging AI applications, offering a comprehensive model for understanding how digital leadership influences employee well-being in high-pressure IT environments. Data collected from 511 IT professionals across major Chinese technology hubs were analyzed using SMART-PLS.

Utility of Multiclass Machine Learning Algorithms in Predicting Same-Day Discharge Following Primary Total Knee Arthroplasty.

Introduction: Length of stay (LOS) is a substantial driver of costs following primary total knee arthroplasty (TKA), leading to increased efforts targeting same-day discharge. However, patient selection for same-day discharge TKA remains a challenge, with 7 to 49% of patients failing to achieve planned same-day discharge with current stratification tools. This study aimed to develop and assess multiclass machine learning models for patient selection for same-day discharge TKA as well as risk for prolonged LOS using a large national patient cohort.

Investigating the Role of Vitamin D in Enhancing Duloxetine and Fluoxetine Efficacy: Mechanistic Insights Into NRF2 Activation, Oxidative Stress, and Neurochemical Modulation.

Depression is a major psychiatric disorder with limited treatment efficacy. Oxidative stress plays a key role in its pathogenesis, and emerging evidence suggests that vitamin D may reduce oxidative damage in neurological conditions. However, its role in modulating antioxidant enzymes and Nrf2 expression in depression remains unclear.

Measurement-Based Care to Enhance Antidepressant Treatment Outcomes in Major Depressive Disorder: A Randomized Clinical Trial.

Importance: Measurement-based care (MBC) guides clinical decisions through structured monitoring of symptoms and adverse effects. Although MBC has been associated with improved outcomes in major depressive disorder (MDD), its effectiveness in low- and middle-income countries (LMICs) remains understudied.

Objective: To assess whether MBC accelerates the resolution of depressive symptoms compared with standard care among adults with MDD in Pakistan.

First Complete Genome Sequence of Palo Verde Broom Emaravirus, Virus-Derived siRNA Signatures, and Phytohormone-Metabolite Profiling of Witches' Broom-Affected Palo Verde Trees.

Witches' broom disease of blue palo verde () was reported more than sixty years ago. Characteristic symptoms consist of dense clusters of shortened, brittle branches and stunted leaves. The suspect causal agent has been identified as palo verde broom virus (PVBV), genus, , family, .

Development of a Predictive Model for Therapy Response in Advanced-Stage Cervical Cancer Using Apparent Diffusion Coefficient (ADC) Value and Quantitative T2 Tumor on MRI: Correlation with Survivin Expression.

Objective: The aims of this study are to optimize Magnetic Resonance Imaging (MRI) as a predictive modality for therapy response in advanced-stage cervical cancer and to identify predictors of this response in relation to survivin expression.

Methods: This case-control study was conducted from January 2023 to May 2024, with total 35 subjects. The target population comprised patients with stages IIB to IIIC2 (FIGO 2018) cervical cancer.

Semantic web ontology for structured knowledge representation and clinical decision support in eye diseases.

Vision is a vital sense that allows people to interact with their surroundings and carry out tasks efficiently while maintaining safety and independence. At least 2.2 billion people globally suffer from blindness or vision impairment, of which more than 1 billion cases are avoidable or untreated because they lack access to eye care services.

Sustainable Removal of Metaldehyde Pesticide via Modified Cellulose Adsorbents.

In this study, commercial, plant-based, and paper-based cellulose acetate (CCA) was modified to develop an efficient adsorbent for removing metaldehyde (MD) from aqueous solutions. The modified commercial CCA exhibited the best performance and was selected for further characterization using FTIR, EDX, SEM, and XRD. Batch experiments were conducted to assess the effects of parameters such as contact time (10-100 min), initial MD concentration (10-100 mg/L), adsorbent dosage (0.

Whole exome sequencing identifies a novel variant causing Neurodegeneration with Brain Iron Accumulation syndrome (NBIA) in a consanguineous Pashtun family.

Neurodegenerative disorders pose a significant public health problem. Among these, neurodegeneration with brain iron accumulation syndrome (NBIA) is particularly challenging because even MRI imaging findings can be subtle. Understanding the genetic basis of NBIA is, therefore, crucial for early diagnosis.

Exploring novel amides as efflux pump inhibitors for overcoming antibiotic resistance in multidrug-resistant .

Background And Objectives: , a multidrug-resistant bacterium, represents a considerable risk in healthcare environments owing to its capacity to induce various infections. The resistance of is frequently linked to efflux pumps that actively remove antibiotics from the bacterial cell. This study investigates novel amide compounds as potential alternatives to address isolates exhibiting multidrug resistance mediated by efflux pumps.

Unveiling genetic diversity and population structure in lentil (Lens culinaris) germplasm through scot markers.

Background: Lentil (Lens culinaris) is extensively cultivated for its edible seeds and plays an important role in food security and sustainable agriculture. Understanding the genetic diversity and population structure of lentil germplasm is crucial for breeding programs and for effective conservation of genetic resources.

Methods And Results: In this study, the genetic variation and population structure of 96 lentil accessions were assessed using Start Codon Targeted (SCoT) markers.

Effect of Marine-Derived Scallop Peptide Hydrolysate on Immune Modulation and Gut Microbiota Restoration in Cyclophosphamide-Induced Immunosuppressed Mice.

Cyclophosphamide (CTX), a chemotherapy agent, can weaken immune responses and disrupt gut microbiota, resulting in dysbiosis and inflammation. The gut microbiota, a composite community of microorganisms, plays a central role in regulating metabolism, supporting biological functions, and maintaining immune balance. Dysbiosis may lead to various systemic diseases and metabolic issues.

Phthalate ester contamination in groundwater at the Himalayan-Potohar Interface: health risks in Rawalpindi, Pakistan.

Phthalate esters (PAEs) are synthetic chemicals widely used as plasticizers, leading to their presence as environmental contaminants with potential health risks. This study investigates the occurrence and concentration of three phthalate esters (PAEs), dibutyl phthalate (DBP), diethyl phthalate (DEP), and dimethyl phthalate (DMP), in groundwater from Rawalpindi City, Pakistan. Fifteen samples were collected and analyzed using liquid-liquid extraction with dichloromethane and gas chromatography-mass spectrometry (GC/MS).

Do Work Schedule and Work Position have an Impact on Fatigue among Geothermal Workers during the COVID-19 Pandemic? An Analysis Using Structural Equation Modeling.

Objectives: This study aimed to examine the impact of work schedule and work position on fatigue levels among employees at a private geothermal firm in Indonesia during the COVID-19 pandemic. The company has modified its work schedule considering the COVID-19 epidemic to ensure a continuous supply of energy and meet the needs of the public.

Methods: In this cross-sectional study, the dependent variable is fatigue, which is classified as a latent variable.

Preparation, Characterization and Removal of Acid Blue 129 and Erioglaucine Dyes from Aqueous Solution by Corn Cob Based Activated Carbon.

Herein, corn cobs (maize) have been converted into an activated carbon by subjecting to carbonization which were then treated with 1:1 solution of HCl and HNO and finally passed through CH solution and finally activated at a high temperature of 400◦C. The obtained activated sample was subjected to XRD, EDX, and SEM analysis. The surface area was estimated as 913 m/g using a reported method in literature.

Endometriosis Can Cause Gastric Obstruction.

Introduction: Gastric outlet obstruction is commonly associated with malignancies and benign conditions such as peptic ulcer disease and Crohn's disease. This report presents an uncommon instance of gastric endometriosis leading to gastric outlet obstruction, a condition that should be considered in the differential diagnosis.

Case Description: A 37-year-old female presented with persistent postprandial vomiting occurring approximately 30 minutes after meals, along with significant weight loss of 25.

May-Thurner Syndrome: Is It on Our Radar?

May-Thurner syndrome (MTS) is a vascular condition in which the right iliac artery compresses the left iliac vein against the lumbar spine. MTS can present as either acute or chronic deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE). We present the case of a 61-year-old female with a medical history of unprovoked DVT on rivaroxaban, who presented with pain and swelling of the left lower limb, associated with shortness of breath for two weeks.

Synthesis and characterization of chitosanyl-N-(Naphthalene-1-yl-amine)acetimidamide as a novel adsorbent for effective removal of bromophenol blue from the aqueous medium.

In the present study, Chitosanyl-N-(Naphthalene-1-yl-amine)acetimidamide was synthesized and used for the removal of bromophenol blue dye (BPB). The modified chitosan is confirmed by different characterization tools, i.e.

Insights from Lentil Germplasm Resources Leading to Crop Improvement Under Changing Climatic Conditions.

Lentil is an important legume crop globally with an annual production of around 6.3 million tons. Pakistan stands at the 49th position producing 4668 tons of lentil from 7428 hectares with an average yield of 570 kg/ha.

Berberine bridge enzyme-like oxidases orchestrate homeostasis and signaling of oligogalacturonides in defense and upon mechanical damage.

Plant immunity is triggered by endogenous elicitors known as damage-associated molecular patterns (DAMPs). Oligogalacturonides (OGs) are DAMPs released from the cell wall (CW) demethylated homogalacturonan during microbial colonization, mechanical or pest-provoked mechanical damage, and physiological CW remodeling. Berberine bridge enzyme-like (BBE-l) proteins named OG oxidases (OGOXs) oxidize and inactivate OGs to avoid deleterious growth-affecting hyper-immunity and possible cell death.

Eucalyptus wood waste biochar: a green solution for fluoranthene contamination in wastewater.

This study investigates the removal of fluoranthene (Flu) from vehicle-wash wastewater (VWW) using biochar (EWB) derived from eucalyptus wood waste. Analytical techniques such as surface area analysis (SAA), scanning electron microscopy (SEM), and fourier transform infrared spectroscopy (FT-IR) were employed to characterize the EWB. Optimal conditions for Flu adsorption (98.

Molecular mechanisms and breeding strategies for enhancing wheat resilience to environmental stresses: The role of heat shock proteins and implications for food security.

Wheat is a major staple crop that plays a pivotal role in global food security. However, its productivity is increasingly compromised by environmental stresses such as heat, drought, salinity and heavy metal toxicity. The broad understanding of molecular mechanisms responsible for wheat resilience is reviewed, with a particular focus on heat shock proteins (HSPs) as key mediators of stress adjustment.

Exploring the Biodiversity and Anticancer Potential of Fungal Endophytes from Peronema canescens Jack.

Peronema canescens Jack has shown promising anticancer activities. This study set out to investigate the rich biodiversity and potential anticancer properties of fungal endophytes derived from P. canescens.

Interaction of micro and nanoplastics (MNPs) with agricultural stored products and their pests.

Micro and nanoplastics (MNPs) pose significant environmental concerns due to their potential implications for ecosystems and human health. While previous research has primarily focused on the environmental impacts (aquatic ecosystem, soil health) of MNPs, this review investigates their interactions with agricultural stored products, specifically their effects on stored product pests and grain quality. MNPs can infiltrate grains through various pathways, including atmospheric deposition, plastic residues from cultivation, and pest activity.