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http://dx.doi.org/10.1016/j.cgh.2020.11.033 | DOI Listing |
Medicine (Baltimore)
August 2025
Department of Surgery, Social Welfare Organization Saiseikai Imperial Gift Foundation Inc, Saiseikai Kazo Hospital, Kazo, Saitama, Japan.
Rationale: Colorectal cancer (CRC) development is a critical prognostic factor for patients with ulcerative colitis (UC), making its early detection important. However, early detection of CRC is clinically challenging. This case report describes a patient diagnosed with transverse colon cancer and a low-grade appendiceal mucinous neoplasm (LAMN) in the context of pancolitis-type UC.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Lloyd Institute of Management and Technology, Plot No. 11, Knowledge Park- II, Greater Noida, Uttar Pradesh 201308, India.
Starch, a naturally abundant polysaccharide, is widely utilized in various industries, including food, textiles and pharmaceuticals owing to its biocompatibility, biodegradability and versatility. In drug delivery systems, it functions as an excipient, binder and controlled-release agent. However, native starch has several limitations such as poor mechanical strength, low moisture retention and insufficient swelling capacity that restrict its application in advanced formulations.
View Article and Find Full Text PDFCureus
June 2025
Department of Gastroenterology, Digestive Disease Consultants, Orlando, USA.
Granular cell tumors (GCTs) are rare neoplasms of Schwann cell origin that typically exhibit benign behavior but can rarely undergo malignant transformation. Gastrointestinal involvement is uncommon, and colonic localization is particularly rare. We report the case of a 51-year-old African American woman referred for evaluation of iron-deficiency anemia.
View Article and Find Full Text PDFJ Gastrointest Oncol
April 2025
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, USA.
Background: T cell large granular lymphocytic leukemia (T-LGL) is a rare indolent lymphoproliferative disorder caused by aberrantly clonal expansion of cytotoxic T lymphocytes. Active mutations of are the hallmark of this disease. It is commonly associated with autoimmune disorders involving multiple organ systems.
View Article and Find Full Text PDFBenef Microbes
April 2025
Laboratory of Food Chemistry, 4508Wageningen University & Research, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
Intrinsic resistant starch type 3 (RS-3) is retrograded starch that is highly resistant to pancreatic digestion (≥80% RS) and will therefore transit to the colon largely intact. Two gut microbes, known as RS degraders, Ruminococcus bromii ATCC27255 and Bifidobacterium adolescentis L2-32, were studied for their ability to degrade intrinsic RS-3 with defined crystal type and chain length (A-type, degree of polymerisation (DP) 16 or DP 21; B-type, DP 32 or DP 76). Remaining glucose, malto-oligosaccharides and non-degraded insoluble RS-3 were quantified over time and remaining RS-3 was visualized by Scanning Electron Microscopy (SEM) over time and compared to degradation of granular maize and potato starch.
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