Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Infectious hematopoietic necrosis virus (IHNV) is a pathogen of importance for salmonid aquaculture. In this study, we aimed to characterize virus behavior and defense mechanisms developed in rainbow trout (RT, Oncorhynchus mykiss) experimentally infected with isolates belonging to the five described genotypes of IHNV, i.e. L, U, M, E and J. Mortality was monitored for two months, and blood and target organs were sampled at different times post-infection to assess viral load and cellular and humoral immune responses. Profiles of virulence were highly linked to precocious viral replication but also to the innate and specific immunity elicited in the host. Seroneutralization test (SNT) used for specific antibodies detection exhibited reliable results, with efficient cross-neutralization observed in heterologous systems except for the Asian representative. These data bring new insights about IHNV/RT interaction and reinforce the interest of SNT as preventive and epidemiological tool.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.virol.2020.09.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Neuroanatomical profiling of the rainbow trout brain parenchyma and meninges reveals specialized immune niches and region-specific hubs for bacterial immune surveillance.
Dev Comp Immunol
September 2025
Center for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA. Electronic address:
Several studies have described immune responses in the teleost brain and meninges during infection, however, fundamental studies that systematically dissect how different regions of the brain maintain immune homeostasis in teleosts are missing. Here we present an in-depth investigation of the immune status of the brain parenchyma and meninges of juvenile rainbow trout (Oncorhynchus mykiss) at the steady state. We dissected four parenchymal brain regions including olfactory bulbs (OB), telencephalon (Tel), optic tectum (OT) and cerebellum (Cer) and its corresponding dorsal meninges.
View Article and Find Full Text PDFGenomic and Transcriptomic Analysis of the Whirling Disease-Resistant Gunnison River Rainbow Trout.
Int J Parasitol
September 2025
School of Public Health, University of Alberta, 357 South Academic Building, Edmonton, Alberta, Canada T6G 2G7. Electronic address:
Whirling disease is a debilitating disease of Rainbow Trout caused by Myxobolus cerebralis. The parasite invasion leads to skeletal deformities, neurological impairment, and high mortality. Since its introduction to North America, M.
View Article and Find Full Text PDFDietary Supplementation of the Rainbow Trout, Oncorhynchus mykiss by Red Ginseng, Panax Ginseng" Powder: Enhancing Effects on Growth, Immunity and Disease Resistance.
Vet Res Commun
September 2025
Department of Animal Science, Chaharmahal and Bakhtiari Agricultural and Natural Resources Research and Education Center, Agricultural Research, Education and Extension Organization (AREEO), Shahrekord, Iran.
This study aimed to determine the effects of dietary red ginseng, Panax ginseng powder (RGP), on the growth performance, immunity, antioxidant system, and disease resistance of the rainbow trout, Oncorhynchus mykiss. Eight experimental groups were established, including a control group and seven groups fed varying levels of ginseng powder (5 to 35 g/kg) over 60 days, followed by a challenge with Streptococcus iniae. The results indicated that ginseng supplementation significantly enhanced growth parameters (P < 0.
View Article and Find Full Text PDFProtective immune response in rainbow trout () against the parasitic nematode .
Front Immunol
September 2025
Laboratory of Aquatic Pathobiology, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.
Introduction: Parasitic nematodes are prevalent in fish populations. The parasites are pathogenic but depress host responses, which limit clearance of the pathogens from the invasion sites. We hypothesized that one of several control strategies, which could augment protection, is immunization of the fish host with parasite antigens prior to live pathogen exposure.
View Article and Find Full Text PDFEvolutionary and molecular characterization of fish specific decoy receptor 3 isoforms (TNFRSF6B.1 and 2) in rock bream (Oplegnathus fascatus).
Dev Comp Immunol
September 2025
Department of Aquatic Life Medicine, Gangneung-Wonju National University, Gangneung, Korea. Electronic address:
TNFRSF6B, commonly referred to as decoy receptor 3, interacts with TNFSF6, TNFSF14, and TNFSF15, thereby imparting anti-apoptotic and anti-inflammatory properties. This study identifies two isoforms, TNFRSF6B.1 and TNFRSF6B.
View Article and Find Full Text PDF