Publications by authors named "Sungjae Ko"
TNFRSF6B, commonly referred to as decoy receptor 3, interacts with TNFSF6, TNFSF14, and TNFSF15, thereby imparting anti-apoptotic and anti-inflammatory properties. This study identifies two isoforms, TNFRSF6B.1 and TNFRSF6B.
View Article and Find Full Text PDFIn this study, heavy chain genes of IgD and IgT were sequenced and characterized their gene expression in rock bream (Oplegnathus fasciatus). Rock bream (RB)-IgD cDNA is 3319 bp in length and encodes a leader region, variable domains, a μ1 domain, and seven constant domains (CH1-CH7). A membrane-bound (mIgT) and secretory form (sIgT) of RB-IgT cDNAs are 1902 bp and 1689 bp in length, respectively, and encode a leader region, variable domains, four constant domains (CH1-CH4) and C-terminus.
View Article and Find Full Text PDFFunctional characterization of a novel tumor necrosis factor gene (TNF-New) in rock bream (Oplegnathus fasciatus).
Dev Comp Immunol
February 2022
Article Synopsis
- Scientists found a special gene called RB-TNFN in rock bream fish, which is similar to a gene found in other fish and some mammals.
- The RB-TNFN gene does important work in the fish's immune system and is mostly active in the liver, helping the fish respond to infections.
- When the fish were vaccinated or injected with certain substances, the RB-TNFN gene and other immune genes became super active, showing how well the fish's body can fight off sickness.