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Water quality is one of the key determinants for assessing effectiveness and success of water diversions, but rarely studied at a spatial scale that crosses large river basins. Multiple statistical methods and the water quality index (WQI) were used to assess overall condition and detect spatiotemporal patterns of water quality in a series of impounded lakes along the Eastern Route of China's South-to-North Water Diversion Project. Principal components analysis and analysis of variances identified three groups with distinct water quality characteristics: upstream Gaoyou Lake and Hongze Lake showing relatively higher nutrients, turbidity, and total suspended solids; downstream Dongping lake and Donghu Lake showing higher conductivity, total hardness, and chloride; and Luoma Lake and Nansi Lake intermediate between the two former groups. The WQI indicated overall "Good" water quality with an improving trend from upstream to downstream lakes. The upstream Gaoyou Lake had over 55% of the monitoring sites with "Moderate" water quality in all the seasons. Management should focus on preventing high nitrogen, phosphorus, turbidity, and total suspended solids in upstream lakes, high chloride in downstream lakes, high nitrogen during water diversion seasons, and high phosphorus during non-water diversion seasons. These findings greatly improved our understanding of the spatiotemporal water quality patterns of the impounded lakes, and can be used to develop water quality management strategies. This study exemplifies a methodology for investigating and securing water quality for inter-basin water transfer projects.
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http://dx.doi.org/10.1016/j.watres.2020.116275 | DOI Listing |
Genome Biol
September 2025
Fisheries Research Institute, Sichuan Academy of Agricultural Sciences, Chengdu, 611730, China.
Background: Fish are the largest group of vertebrates. Studying the characteristics, functions, and interactions of different fish cells is important for understanding their roles in disease and evolution. However, most single cell RNA-seq studies in fish are restricted to a few specific organs, leaving a comprehensive cell landscape that aims to characterize the heterogeneity and connections among body-wide organs largely unexplored.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
School of Materials Engineering, Changzhou Vocational Institute of Industry Technology, Changzhou, 213000, People's Republic of China.
A multi-indicator framework was developed to resolve multi-source pollution in highly urbanized rivers, demonstrated in the Qinhuai River Basin, Nanjing, China. Water quality index (WQI) stratification was integrated with dissolved organic matter (DOM) fluorescence components, hydrochemical ions, and conventional parameters and analyzed using positive matrix factorization (PMF). Correlation analysis further elucidated source compositions and interactions.
View Article and Find Full Text PDFEnviron Sci Technol
September 2025
State Key Laboratory of Advanced Environmental Technology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
The potential of PM to cause lung cancer has been well established; however, evidence regarding which specific components are responsible remains limited. We investigated dissolved organic matter (DOM) in PM using high-resolution mass spectrometry (HRMS) and cellular DNA damage assays to elucidate molecular composition and sources of carcinogenic components. Our analysis revealed hundreds of genotoxic compounds, with condensed aromatic amines predominating in number, abundance, and contribution to overall genotoxicity.
View Article and Find Full Text PDFInt J Pharm
September 2025
Life Quality (LQ) Engineering Interest Group, School of Chemical and Environmental Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu Province 215123, China. Electronic address:
Gastrointestinal (GI) physiological variability significantly influences dissolution and bioavailability of non-disintegrating solid drug systems. This study employed the dynamic human stomach-intestine (DHSI-IV, branded as NERDT) system to characterize how gastric emptying kinetics and intestinal environmental dynamics affect drug release, using extended-release metformin matrix tablets (Glucophage XR®) and metformin osmotic pump tablets (Nida®) as model formulations. The DHSI-IV (NERDT) system accurately simulated three fasting-state gastric emptying profiles (30-120 min complete emptying) with excellent fit to the modified Elashoff model (R = 0.
View Article and Find Full Text PDFMar Environ Res
September 2025
Functional Biology Department (Ecology Area), Faculty of Biology, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Balancing socio-economic development with environmental quality in estuaries requires reliable tools for ecological assessment and informed management. Although various biological and (geo)chemical indices have been formulated to evaluate ecological quality status (EcoQS), transitional systems such as estuaries remain challenging to assess due to steep natural gradients and intense anthropogenic pressures, which can compromise the effectiveness of conventional indices. This study applied a practical, multi-criteria sediment assessment to evaluate benthic EcoQS in the Sado estuary, SW Portugal - a socio-ecological system strongly influenced by human activity.
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