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http://dx.doi.org/10.1007/s00259-020-04985-7 | DOI Listing |
CNS Neurol Disord Drug Targets
September 2025
College of Pharmacy, National University of Science and Technology, Muscat, Oman.
Neurological disorders are complex conditions characterized by impairment of the nervous system, affecting motor, cognitive, and sensory functions. Current treatments meet substantial obstacles, primarily due to the difficulty of transporting drugs across the blood-brain barrier and ineffective therapy for nerve regeneration. Emerging technologies, such as electrospinning, offer innovative solutions to overcome these challenges.
View Article and Find Full Text PDFJ Am Chem Soc
August 2025
Cluster of Excellence livMatS @ FIT-Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg, Georges-Köhler-Allee 105, 79110 Freiburg, Germany.
Mucins are highly complex glycoproteins that form protective and lubricating barriers around epithelial surfaces, e.g., in the respiratory tract, to protect against pathogens.
View Article and Find Full Text PDFWien Med Wochenschr
August 2025
Department of Dermatology and Venereology, Medical University of Graz, Auenbruggerplatz 8, 8036, Graz, Austria.
Syphilis is a systemic sexually transmitted infection caused by the invasive bacterium Treponema pallidum. The diagnosis remains challenging since the disease is labeled as "the great imitator" due to its broad clinical and histopathological appearances. Due to a significant rise in its incidence rates, syphilis should always be considered as a differential diagnosis of any painless, newly developed, oropharyngeal ulcerated lesion.
View Article and Find Full Text PDFCureus
July 2025
Department of Neurology, University Hospital of Agadir, Agadir, MAR.
Background Syphilis is a complex disease with a wide range of clinical manifestations. Neurosyphilis, a complication affecting the central nervous system, can occur at any stage of the disease, particularly in untreated cases. While classical forms are well documented, atypical presentations remain underrecognized, leading to diagnostic delays.
View Article and Find Full Text PDFArthritis Rheumatol
August 2025
Department of Ophthalmology and Visual Science, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan.