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Herein, a boronic acid-based sensor was reported selectively to recognize Pd ion. The fluorescence intensity increased 36-fold after sensor binding with 2.47 × 10 M of Pd ion. It was carried out in the 99% aqueous solution for binding tests, indicating sensor having good water solubility. In addition, it is discernible that Pd ion turned on the blue fluorescence of sensor under a UV-lamp (365 nm), while other ions (Ag, Al, Ba, Ca, Cr, Cd, Co, Cs, Cu, Fe, Fe, K, Li, Mg, Mn, Na, Ni and Zn) did not show the similar change. Furthermore, sensor has a low limit of detection (38 nM) and high selectivity, which exhibits the potential for the development of Pd recognition in practical environments.
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http://dx.doi.org/10.1016/j.bmcl.2020.127397 | DOI Listing |
Food Chem
August 2025
School of Chemistry and Chemical Engineering, Anhui University of Technology, Maanshan 243032, PR China; Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, Yulin Normal University, Yulin 537000, China. Electronic address:
Ellagic acid (EA) exhibits remarkable in-vivo bioactivity and antioxidant properties. EA is also a skin-whitening agent. Accurate quantification of EA is crucial for the effective use of EA-rich foods and cosmetics.
View Article and Find Full Text PDFMolecules
July 2025
Department of Chemistry of the College of Staten Island, and The PhD Program in Chemistry of Graduate Center, The City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA.
Glucose-responsive insulin delivery systems that effectively regulate insulin retention and release in response to real-time fluctuation of glucose levels are highly desirable for diabetes care with minimized risk of hypoglycemia. Herein, we report a class of glucose-sensitive copolymer microgels, prepared from a simple one-pot precipitation copolymerization of 4-vinylphenylboronic acid (VPBA), 2-(dimethylamino) ethyl acrylate (DMAEA), and oligo(ethylene glycol) methyl ether methacrylate (M = 300, MEOMA), for gated glucose-responsive insulin release within the physiologically desirable glucose level range. The composition of the p(VPBA-DMAEA-MEOMA) copolymer microgels were analyzed using NMR and FTIR spectra.
View Article and Find Full Text PDFACS Nano
July 2025
Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, PR China.
2,5-Furandicarboxylic acid (FDCA)-based polyesters are among the most promising materials for achieving sustainability and recyclability of plastics in the current era of the energy crisis. However, it is difficult to construct one single polyester with integrated high strength, toughness, and gas barrier properties. Inspired by the biomineralization process of nacre, herein we develop a nanoconfined crystallization strategy to manufacture innovative FDCA-based pseudo-mineralization polyester (denoted as PMP) that combines ultrahigh mechanical strength, toughness, and excellent barrier properties.
View Article and Find Full Text PDFJ Med Chem
July 2025
Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand 247667, India.
The global threat posed by multidrug-resistant bacteria, particularly those producing KPC-2 carbapenemases, has compromised the effectiveness of carbapenems, the last-resort antibiotics. To address this, we utilized a bioisosteric replacement approach to synthesize phenylboronic acid (PBA) derivatives targeting KPC-2. The enzyme kinetics study revealed that electron-withdrawing substituents enhanced the residence time of lead compounds, enhancing KPC-2 inhibition.
View Article and Find Full Text PDFACS Chem Biol
July 2025
Université Paris-Saclay, CNRS, Institut de Chimie Moléculaire et des Matériaux d'Orsay, UMR CNRS 8182, 91405 Orsay, France.
Hydrogen peroxide (HO) is a crucial reactive oxygen species (ROS) involved in regulating both physiological and pathological processes. Excessive HO production can lead to oxidative stress, contributing to aging, cancer, and neurodegenerative diseases. In contrast to other ROS exhibiting short lifespans, HO is relatively stable, and its spatial and temporal dynamics are central to understanding its pathophysiological role.
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