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http://dx.doi.org/10.1038/s41422-020-0384-8 | DOI Listing |
Protein Cell
August 2025
Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200433, China.
Cardiovascular disease (CVD) research is hindered by limited comprehensive analyses of plasma proteome across disease subtypes. Here, we systematically investigated the associations between plasma proteins and cardiovascular outcomes in 53,026 UK Biobank participants over a 14-year follow-up. Association analyses identified 3,089 significant associations involving 892 unique protein analytes across 13 CVD outcomes.
View Article and Find Full Text PDFAlzheimers Dement
September 2025
Department of Neurology, Beijing TianTan Hospital, Capital Medical University, Beijing, China.
Cognitive impairment and dementia, including Alzheimer's disease (AD), pose a global health crisis, necessitating non-invasive biomarkers for early detection. This review highlights the retina, an accessible extension of the central nervous system (CNS), as a window to cerebral pathology through structural, functional, and molecular alterations. By synthesizing interdisciplinary evidence, we identify retinal biomarkers as promising tools for early diagnosis and risk stratification.
View Article and Find Full Text PDFHum Brain Mapp
September 2025
Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, Georgia, USA.
Investigating neuroimaging data to identify brain-based markers of mental illnesses has gained significant attention. Nevertheless, these endeavors encounter challenges arising from a reliance on symptoms and self-report assessments in making an initial diagnosis. The absence of biological data to delineate nosological categories hinders the provision of additional neurobiological insights into these disorders.
View Article and Find Full Text PDFCurr Dev Nutr
September 2025
Department of Sport, Exercise and Nutrition, Atlantic Technological University, Galway, Ireland.
Background: Nutrition underpins athletic performance, enhancing training, reducing injury risk, and accelerating recovery. In the event of an injury, performance dietitians (PDs) and nutritionists' (PNs) play a vital role by tailoring nutritional strategies to support tissue repair, optimize athlete's recoveries, and return to play.
Objectives: This study explored nutritional strategies recommended and employed by Irish PDs and PNs to assess, manage, and support athletes during the initial stages of sports-related injuries.
Med Acupunct
August 2025
Graduate Institute of Acupuncture Science, China Medical University, Taichung City, Taiwan.
Background: The safety of acupuncture treatments is crucial for patients. Although acupuncture is generally considered a relatively safe therapeutic modality, acupuncture-related adverse events cannot be entirely avoided. The development and implementation of effective preventive strategies are essential for enhancing clinical safety.
View Article and Find Full Text PDF