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The aim of this work was to determine the total concentration and the effect of in vitro digestion on the bioaccessible fraction of aluminum (Al) in 35 different cereal-based baby food samples and estimate the exposure to this element considering the consumption of this product. Total Al content was determined by inductively coupled plasma optical emission spectrometry after oxidative microwave digestion. An in vitro digestion method was applied and optimized to evaluate the bioaccessible fraction. The methods performance was efficient for both approached analysis and presented limits of detection and quantitation of 53 μg kg and 89 μg kg, respectively. Total concentration and bioaccessibility varied according to the product composition (rice, oat, wheat, barley, corn, multicereal and fruit). Multicereals and fruit-based (plum) cereals presented the highest total Al concentrations (8.82 mg kg and 7.49 mg kg, respectively), whilst lower values were observed for corn and rice flour cereals (0.92 mg kg and 1.09 mg kg, respectively). The bioaccessible fraction varied from 1.5% to 10.4% in the evaluated samples. Exposure to Al was estimated and compared with the Provisional Tolerable Weekly Intake (PTWI) of 2 mg kg body weight. The results showed that the daily consumption of three portions of cereals contributes up to 10.48% of the PTWI, when considering the total Al concentration reported in this study.
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http://dx.doi.org/10.1016/j.foodres.2019.108965 | DOI Listing |
Environ Sci Technol
September 2025
School of Environment, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Normal University, Xinxiang 453007, China.
To characterize the bioaccessibility of inhaled organophosphate esters (OPEs) in the respiratory tract, we employed a highly idealized mouth-throat model to investigate the occurrence, distribution, and deposition of 17 OPEs in airborne particulate matter (PM, PM, and PM; = 80 pairs) and gas phases ( = 48) under gradient temperature and humidity. OPEs concentrations were also measured in exhaled breath condensate (EBC; = 50) and sputum ( = 30) from 30 adults. Total median ∑OPEs concentrations in inhaled air were 4.
View Article and Find Full Text PDFPlant Foods Hum Nutr
September 2025
REQUIMTE/LAQV, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
The growing interest in prebiotic ingredients has led to the valorization of agri-food by-products, such as coffee silverskin, known for its richness in dietary fiber and health-promoting compounds. This study evaluated the impact of in vitro simulation of gastrointestinal digestion on the chemical composition (carbohydrates, caffeine, and chlorogenic acids) and prebiotic potential (probiotic growth, organic acid production, pH, and antioxidant activity) of milled coffee silverskin. The results show stability of polysaccharides during digestion, while caffeine and 5-caffeoylquinic acid were partially released into the bioaccessible fraction.
View Article and Find Full Text PDFToxics
August 2025
Fujian Key Laboratory of Toxicant and Drug Toxicology, Medical College, Ningde Normal University, Ningde 352100, China.
Soil co-contamination with antimony (Sb) and arsenic (As) presents significant ecological and human health risks, demanding effective stabilization solutions. This study evaluated iron-manganese-modified hydrochar (FMHC) for synergistic Sb-As stabilization in contaminated smelter soils. Through 60-day natural aging and 30 accelerated aging cycles, we assessed stabilization performance using toxicity leaching tests (acid/water/TCLP), bioavailable fraction analysis, bioaccessibility assessment, and Wenzel sequential extraction.
View Article and Find Full Text PDFToxics
July 2025
Immunobiology for Aquaculture Group, Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain.
This study evaluates the potential health risks posed by geogenic arsenic in environments suitable for leisure activities, such as walking, bathing, and playing, for adults and children alike, as well as in neighbouring agricultural areas. The study includes an analysis of environmental characteristics and the main stream originating in the adjacent mining area, with water and sediment samples taken. The study area is representative of other areas in the vicinity of the Mar Menor Lagoon, which is one of the largest and most biodiverse coastal lagoons in the Mediterranean Sea.
View Article and Find Full Text PDFFront Nutr
August 2025
Food Chemistry Lab, Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, Italy.
Objective: We investigated the phytochemical composition, gastrointestinal bioaccessibility, and protective effects against mycotoxin-induced toxicity of L. flower, a botanical species traditionally used in European herbal medicine.
Methods: flower samples were collected from the Majella National Park and chemically characterized using HPLC-PDA and NMR metabolomics, revealing the presence of abundant bioactive compounds (iridoids, secoiridoids, and xanthones), as well as quantifying the levels of amino acids, organic acids, and sugars.