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The marine environment encompasses a huge biological diversity and can be considered as an underexplored location for prospecting bioactive molecules. In this review, the current state of art about antimicrobial molecules from marine bacteria has been summarized considering the main phylum and sources evolved in a marine environment. Considering the last two decades, we have found as most studied group of bacteria producers of substances with antimicrobial activity is the Firmicutes phylum, in particular strains of the genus. The reason for that can be attributed to the difficult cultivation of typical Actinobacteria from a marine sediment, whose members are the major producers of antimicrobial substances in land environments. However, a reversed trend has been observed in recent years with an increasing number of reports settling on Actinobacteria. Great diversity of chemical structures have been identified, such as fijimicyns and lynamicyns from Actinomycetes and macrolactins produced by .
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http://dx.doi.org/10.1080/07388551.2019.1710457 | DOI Listing |
BMB Rep
September 2025
Basic Research Laboratory, Department of Physiology, College of Medicine, Smart Marine Therapeutic Center, Cardiovascular and Metabolic Disease Core Research Center, Inje University, Busan 47392, Korea; Department of Health Science and Technology, College of Medicine, Inje University, Busan 47392, K
Patients with multiple myeloma develop resistance to thalidomide during therapy, and the mechanisms to counteract thalidomide resistance remain elusive. Here, we explored the interaction between cereblon and mitochondrial function to mitigate thalidomide resistance in multiple myeloma. Measurements of cell viability, ATP production, mitochondrial membrane potential, mitochondrial ROS, and protein expression via western blotting were conducted in vitro using KSM20 and KMS26 cells to assess the impact of thalidomide on multiple myeloma.
View Article and Find Full Text PDFElectrophoresis
September 2025
Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, and Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, People's Republic of China.
Foodborne pathogenic bacteria always threaten human health. Flavonoids are commonly used in antibacterial applications. Studying the antibacterial effect of flavonoids on bacteria is significant.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Department of Biology & CESAM-Centre for Environmental and Marine Studies, University of Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro, Portugal.
Maize (Zea mays L.) is one of the world's most widely cultivated and economically important cereal crop, serving as a staple food and feed source in over 170 countries. However, its global productivity is threatened by late wilt disease (LWD), a disease caused by Magnaporthiopsis maydis, that spreads through soil and seeds and can cause severe yield losses.
View Article and Find Full Text PDFMicrobiol Res
September 2025
Key Laboratory of Marine Ecosystem Dynamics, Second Institute of Oceanography, Ministry of Natural Resources, Hangzhou 310012, China.
Cadmium (Cd) contamination in coastal regions poses severe environmental risks, yet bacterial defense mechanisms against Cd remain poorly understood. This study unveils distinct tolerant strategies of two highly Cd-tolerant bacteria isolated from the Yangtze River estuary: Comamonas sp. Y49 and Aeromonas sp.
View Article and Find Full Text PDFMar Pollut Bull
September 2025
Department of Ocean Engineering, Pukyong National University, 45 Yongso-ro, Nam-Gu, Busan 48513, Republic of Korea. Electronic address:
Coastal sediments in semi-enclosed bays are particularly susceptible to contamination due to limited water circulation and ongoing contaminant input. In Masan Bay, a heavily impacted coastal area in Korea, sediment remediation is essential to alleviate the effects of organic enrichment and hypoxia. This study investigated the effectiveness of oyster shell capping as an in-situ remediation technique by assessing its impact on sediment environment, microbial communities, and macrobenthic fauna.
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