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http://dx.doi.org/10.1016/j.jcmg.2019.07.020 | DOI Listing |
Int J Surg
September 2025
Department of Gynecology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Background: Ovarian cancer remains the most lethal gynecological cancer, with fewer than 50% of patients surviving more than five years after diagnosis. This study aimed to analyze the global epidemiological trends of ovarian cancer from 1990 to 2021 and also project its prevalence to 2050, providing insights into these evolving patterns and helping health policymakers use healthcare resources more effectively.
Methods: This study comprehensively analyzes the original data related to ovarian cancer from the GBD 2021 database, employing a variety of methods including descriptive analysis, correlation analysis, age-period-cohort (APC) analysis, decomposition analysis, predictive analysis, frontier analysis, and health inequality analysis.
Metab Brain Dis
September 2025
Department of Neuroscience, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Brain ischemia is a major global cause of disability, frequently leading to psychoneurological issues. This study investigates the effects of 4-aminopyridine (4-AP) on anxiety, cognitive impairment, and potential underlying mechanisms in a mouse model of medial prefrontal cortex (mPFC) ischemia. Mice with mPFC ischemia were treated with normal saline (NS) or different doses of 4-AP (250, 500, and 1000 µg/kg) for 14 consecutive days.
View Article and Find Full Text PDFJ Eval Clin Pract
September 2025
School of Public Health, Wuhan University, Wuhan, China.
Background: Social support can have health benefits but may also pose risks for the elderly, particularly those facing conflicts and network disruptions. Understanding the short and long-term mental health effects, especially in elderly individuals with chronic illnesses, is crucial due to global depression concerns. Yet, research is limited, with gaps in exploring different social disruption scenarios and lacking comprehensive multi-period data analysis.
View Article and Find Full Text PDFFront Public Health
September 2025
Gülhane Faculty of Physiotherapy and Rehabilitation, University of Health Sciences, Ankara, Türkiye.
Background: The increasing prevalence of sports injuries among young female volleyball players, driven by biomechanical and hormonal factors, necessitates effective prevention strategies. Screening tools like the Functional Movement Screen (FMS) and Star Excursion Balance Test (SEBT) often show inconsistent predictive validity for injury risk in this population. This study investigates associations between FMS, SEBT, agility, and muscle strength with injury risk in young female volleyball players to refine prediction models and inform targeted interventions.
View Article and Find Full Text PDFClin Interv Aging
September 2025
Department of Nephrology, Huadong Hospital, Fudan University, Shanghai, People's Republic of China.
Objective: This study evaluates cardiac function in older adults with T2DM and preserved LVEF using two-dimensional speckle-tracking echocardiography to explore the risk factors associated with subclinical left ventricular systolic dysfunction (GLS <18%) in this population.
Methods: All patients (n = 87, aged 60 years and above) and controls (n = 20) underwent clinical assessment and echocardiography, including GLS assessment.
Results: Univariate analysis identified gender (OR 3.