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http://dx.doi.org/10.11477/mf.1436204004 | DOI Listing |
J Am Heart Assoc
September 2025
Department of Neurosurgery Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China.
Background: The cellular composition and molecular mechanisms of the pathological arteries in Moyamoya disease (MMD) remain poorly understood. To improve our understanding of pathogenesis in MMD, we aimed to comprehensively map the cellular composition and molecular alterations within the pathological arteries of patients with MMD.
Methods: Superficial temporal artery samples were collected from patients with MMD (n=2) and healthy controls (n=3), yielding a total of 26 371 cells that were used for single-cell RNA sequencing.
Ophthalmol Glaucoma
September 2025
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida, United States. Electronic address:
Purpose: To evaluate superficial microvascular deficits of glaucomatous eyes with wide-field optical coherence tomography angiography (OCTA) and Euclidian distance (ED) analysis.
Design: Cross-sectional study.
Subjects: Swept-source OCTA (SS-OCTA) images of healthy and glaucomatous eyes.
Anat Sci Int
September 2025
Department of Radiology, University of Health Sciences, Istanbul Haseki Training and Research Hospital, Istanbul, Turkey.
The transverse facial artery is a key vascular structure supplying the lateral face and is critically important in surgical procedures such as facelifts, facial trauma repair, and injectable treatments. However, detailed anatomical studies on the transverse facial artery remain scarce. This study aimed to comprehensively evaluate the anatomical variations, depth, branching patterns and clinical significance of the transverse facial artery (TFA) using both cadaveric dissection and computed tomography angiography (CTA).
View Article and Find Full Text PDFBrain Commun
August 2025
CNNP Lab (www.cnnp-lab.com), School of Computing, Newcastle University, Newcastle upon Tyne NE4 5BX, United Kingdom.
Non-invasive neuroimaging is important in epilepsy to help identify cerebral abnormalities. Abnormally reduced fractional anisotropy (FA) in deep white matter (WM) from diffusion-weighted imaging (DWI) is widely reported in large multi-cohort studies across all types of epilepsies. However, abnormalities in FA for superficial WM are rarely investigated in epilepsy.
View Article and Find Full Text PDFEur Radiol
September 2025
Department of Radiology and Imaging Sciences, University of Utah, 30N Mario Capecchi Drive, 2 South, Salt Lake City, UT, USA.
Alzheimer disease (AD) is the most common dementing disorder, affecting 55 million people worldwide. Brain MRI plays an integral role in the diagnostic evaluation of patients with cognitive symptoms. When interpreting brain MRI for cognitive impairment, radiologists should assess the following four key features: (1) white matter ischemic burden, (2) structural changes to suggest normal pressure hydrocephalus, (3) locoregional pattern of brain atrophy, and (4) presence of microhemorrhage or superficial siderosis, particularly for determining eligibility for anti-amyloid monoclonal antibody (MAB) treatment when appropriate.
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