Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: A previous study showed that prebiotics and synbiotics administered in ovo into the egg air cell on the 12th day of incubation enhance the growth and development of chickens. However, the influence of this procedure on the development and efficiency of the innate immune system of broiler chickens is unclear. Therefore, the aim of this study was to evaluate whether the early (on the 12th day of embryo development) in ovo administration of selected prebiotics (inulin - Pre1 and Bitos - Pre2) and synbiotics (inulin + Lactococcus lactis subsp. lactis IBB SL1 - Syn1 and Bitos + L. lactis subsp. cremoris IBB SC1 - Syn2) influences the innate immune system.
Results: Chickens (broiler, Ross 308) that were treated with Pre1 exhibited a decreased H/L ratio on D7, but an increased H/L ratio was observed on D21 and D35. In the remaining experimental groups, an increase in the H/L ratio was observed on D21 and D35. The oxidative potential of leukocytes measured using the NBT test increased on D21 in Pre2 and Syn1 groups. The rate of the phagocytic ability of leukocytes increased in Pre1 and Syn1 groups on D21. The phagocytic index decreased in Pre1 and Syn2 groups on D21 and D35. Concurrently, the count of WBC in circulating blood decreased on D21 in Pre1, Pre2, and Syn1 groups. The hematocrit value was increased in Syn1 chickens on D21, in Pre1 chickens on D35, and in Syn2 chickens on both time points.
Conclusions: Early in ovo treatment of chicken embryos with prebiotics and synbiotics may temporarily modulate not only the production/maturation of leukocytes but also their reactivity.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448256 | PMC |
| http://dx.doi.org/10.1186/s12917-019-1850-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Correction: Exploring the gut microbiome: probiotics, prebiotics, synbiotics, and postbiotics as key players in human health and disease improvement.
Food Sci Biotechnol
October 2025
Department of Food Science and Technology, University of California-Davis, Davis, CA USA.
[This corrects the article DOI: 10.1007/s10068-024-01620-1.].
View Article and Find Full Text PDFProbiotics and non-starch carbohydrates as microecological agents: A review of classification strategies and feed applications.
Int J Biol Macromol
September 2025
Academy of Advanced Carbon Conversion Technology, Huaqiao University, Xiamen, 361021, China; Fujian Provincial Key Laboratory of Biomass Low-Carbon Conversion, Huaqiao University, Xiamen, 361021, China; College of Chemical Engineering, Huaqiao University, Xiamen, 361021, China. Electronic address: l
Over recent decades, the indiscriminate use of antibiotics in animal production to enhance product quality and maximize economic returns has raised critical concerns. However, antibiotic misuse has led to the development of antimicrobial resistance in livestock and poses substantial health risks to humans through drug residue accumulation. In response, nations globally have progressively implemented bans on antibiotic inclusion in animal nutrition, redirecting scientific attention toward antibiotic-free feed additives that maintain or enhance animal health performance.
View Article and Find Full Text PDFProbiotics Co-administered with LCM Enhance Antiepileptic Efficacy in the Experimental Post-traumatic Epilepsy Model.
Neurochem Res
September 2025
Department of Physiology, Hamidiye Faculty of Medicine, University of Health Sciences, Istanbul, Turkey.
The aim of the presented study was to investigate the effects of prebiotic inulin, probiotic VSL#3 (mixture of bacteria from 7 different species and 8 strains) and synbiotic (inulin + VSL#3) supplements applied together with lacosamide (LCM) on post-traumatic epilepsy (PTE). In addition, effectiveness of the relevant treatments on comorbid problems related to learning and memory, anxiety, motor performance and pain threshold that may develop together with seizures due to traumatic brain injury (TBI) and PTE was also examined using behavioral tests. In experiments, adult male Sprague-Dawley rats, divided into 6 groups, were given 30 mg/kg LCM or 1000 mg/kg inulin together with LCM as prebiotic, VSL#3 mixture containing 10 × 10 CFU/kg bacterial colonies as probiotic and (inulin + VSL#3) as synbiotic for 28 days by oral gavage after mild-TBI was induced by weight-drop method and electroencephalogram electrodes were placed.
View Article and Find Full Text PDFEarly-life nutritional additives, household environment, and air pollution in relation to childhood food allergies: A multi-city mother-child study in China.
Environ Int
September 2025
Centre for Molecular Biosciences and Non-communicable Diseases Research, Xi'an University of Science and Technology, Xi'an 710054, China. Electronic address:
Background: Nutritional supplements and environments have been linked with food allergy (FA), but little research has explored their interactions on children's FA.
Objectives: To explore the associations between early-life nutritional supplements, household environmental factors (HEFs), and outdoor air pollutant (OAP) exposures, and their interactions on children's FAs.
Methods: We collected 20,730 surveyed questionnaires from five Chinese cities, covering data on individual characteristics, health outcomes, and HEFs.
Protective Roles of Prebiotics and Probiotics Against Environmental Pollutant-Induced Toxicities: A Systematic Review of Animal Studies.
Mol Nutr Food Res
September 2025
School of Human Nutrition, McGill University, Montréal, Quebec, Canada.
Environmental pollutants, including heavy metals, organic pollutants, and mycotoxins, cause various adverse health effects linked to inflammation and oxidative stress. These toxicities disrupt gut microbiota composition and function, which prebiotics and probiotics may counteract. This study systematically reviewed the effects of prebiotics, probiotics, synbiotics, and commensal gut microbiota on pollutant-induced toxicities in animal models.
View Article and Find Full Text PDF