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Purpose: Juvenile idiopathic arthritis (JIA) frequently affects the temporomandibular joints and may cause dentofacial deformity and dysfunction. The adverse effects of JIA on dentofacial growth, morphology, and function may be due to erosion of the existing mandibular condyle(s), the inhibitory effect of the arthritis on the growing mandible, or both. No algorithm exists for management of JIA-induced skeletal and dental abnormalities; treatment varies widely.
Materials And Methods: On the basis of the available literature and expert opinion obtained by a consensus conference held by the Temporomandibular Joint Juvenile Arthritis (TMJAW) group-a multidisciplinary and multinational clinical and research network dedicated to the diagnosis and management of temporomandibular joint arthritis caused by JIA-we present an algorithm to be used as a conceptual framework for management of dentofacial deformity resulting from JIA.
Results: An algorithm for management of dentofacial deformity resulting from JIA is presented and exemplified by 5 clinical cases.
Conclusions: A standardized algorithm will improve clinical decision making and facilitate outcome research by allowing valid comparisons between published research studies. We emphasize the importance of multidisciplinary evaluation, management, and long-term follow-up.
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http://dx.doi.org/10.1016/j.joms.2019.02.014 | DOI Listing |
J Oral Maxillofac Surg
August 2025
Oral and Maxillofacial Surgeon, João XXIII Hospital, Belo Horizonte, Brazil; Residency Program Director, Oral and Maxillofacial Surgery, João XXIII Hospital, Belo Horizonte, Brazil.
Background: Le Fort I osteotomy (LFIO) may lead to nasolabial changes. Therefore, several techniques have been proposed to minimize these effects, including the subspinal osteotomy, which can preserves perinasal structures.
Purpose: The purpose of this study was to compare the associations between conventional and subspinal LFIO and changes in the nasolabial soft tissues.
Sci Rep
August 2025
Dentofacial Deformities Research Center, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Danshjoo BLVD, Velenjak, Shahid Chamran Highway, Tehran, 1983963113, Iran.
This study assessed the effects of photobiomodulation therapy (PBMT) with different laser wavelengths on the viability and differentiation of periodontal ligament mesenchymal stem cells (PDLMSCs) exposed to zoledronic acid (ZA). In this in vitro study, PDLMSCs were cultured with 5 µM ZA for 48 h and randomly assigned to 6 groups of positive and negative controls, and PBMT with 635 nm (2 and 4 J/cm) and 980 nm (2 and 4 J/cm) lasers. Cell viability was assessed by the methyl thiazolyl tetrazolium (MTT) assay after 24 and 72 h, and mineralized nodule formation was evaluated by Alizarin red staining.
View Article and Find Full Text PDFMed Oral Patol Oral Cir Bucal
August 2025
Department of Morphology Faculty of Medicine, Federal University of Ceará Delmiro de Farias, 1331- Rodolfo Teófilo Zip code: 60430-170, Fortaleza, CE, Brazil
Background: Le Fort I (LFI) osteotomy represents a secure procedure employed for correcting facial deformities and may be coupled with other facial osteotomies. However, notwithstanding professional proficiency, this technique is not exempt from issues or morbidities. Therefore, the objective of this study was to relate the types of vascular complications associated with LFI.
View Article and Find Full Text PDFJ Imaging Inform Med
August 2025
Department of Orthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Orthognathic surgery is often required to address moderate to severe skeletal class II malocclusion, a condition that affects both facial aesthetics and function. Traditional diagnosis relies on cephalometric radiographs and expert evaluation, which can be time-consuming and subject to inter-observer variability. The need for AI-assisted initial screening based exclusively on lateral soft tissue profiles is increasingly recognized, particularly for identifying mandibular retrusion relative to the maxilla.
View Article and Find Full Text PDFClin Exp Dent Res
August 2025
Department of Radiology, School of Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Certain dental diseases in pediatric patients may disturb their sleep, affect their oral health-related quality of life, and result in a negative influence on cognition and behavior. On the other hand, sleep disturbances may also increase the risk or participate in development and progression of dental diseases.
Objective: This narrative review aimed to overview of the bidirectional relationship between common dental diseases and sleep disturbances, as well as the potential mechanisms behind.