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Magnetite-based magnetic nanoparticles have been successfully coupled to an organic system constituted of a fluorescent molecule, a tripeptide specifier and a spacer. The system is able to selectively release the fluorescent molecule upon targeted enzymatic hydrolysis promoted by a lysine/arginine specific protease.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905276 | PMC |
http://dx.doi.org/10.3762/bjnano.9.92 | DOI Listing |
Mikrochim Acta
September 2025
Department of Public Health Laboratory Sciences, College of Public Health, Hengyang Medical School, University of South China, 28 Changsheng West Road, Hengyang, 421001, Hunan, China.
We systematically evaluated the DNA adsorption and desorption efficiencies of several nanoparticles. Among them, titanium dioxide (TiO₂) nanoparticles (NPs), aluminum oxide (Al₂O₃) NPs, and zinc oxide (ZnO) NPs exhibited strong DNA-binding capacities under mild conditions. However, phosphate-mediated DNA displacement efficiencies varied considerably, with only TiO₂ NPs showing consistently superior performance.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Department of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
The exclusive formation of artificial multicomponent assemblies remains a significant challenge, in contrast to the well-established organization observed in natural systems, due to intrinsic entropic constraints. To overcome this limitation, recent efforts have been focused on developing precision self-assembly strategies for the rational construction of such architectures. Here, we construct an ideal complementary pair of 2,2':6',2″-terpyridine (tpy)-based ligands by fine-tuning the substituent bulkiness, which enables the quantitative formation of robust nested cages through efficient dynamic heteroleptic complexation with multivalent coordination.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
Masaryk University, Faculty of Science, Department of Chemistry, Kotlářská 2, Brno, 611 37, Czech Republic.
Structural and magnetic properties of ultra-small tetrahedron-shaped iron oxide nanoparticles were investigated using density functional theory. Tetrahedral and truncated tetrahedral models were considered in both non-functionalized form and with surfaces passivated by pseudo-hydrogen atoms. The focus on these two morphologies reflects their experimental relevance at this size scale and the feasibility of performing fully relaxed, atomistically resolved first-principles simulations.
View Article and Find Full Text PDFJ Mater Chem B
September 2025
Biomolecular Physics Department, Faculty of Physics, Babes-Bolyai University, 1 M. Kogalniceanu Street, 400084, Cluj-Napoca, Romania.
Magnetic nanoparticles are widely explored in biomedical applications, particularly as MRI contrast agents and for magnetic hyperthermia. However, their photothermal capabilities under near-infrared (NIR) irradiation remain underexplored in realistic, tissue-like environments. This study provides a comprehensive assessment of ultrasmall FeO nanoparticles (9.
View Article and Find Full Text PDFSmall Methods
September 2025
Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, 100871, China.
Understanding the brain's complexity and developing treatments for its disorders necessitates advanced neural technologies. Magnetic fields can deeply penetrate biological tissues-including bone and air-without significant attenuation, offering a compelling approach for wireless, bidirectional neural interfacing. This review explores the rapidly advancing field of magnetic implantable devices and materials designed for modulation and sensing of the brain.
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