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This study was aimed to examine the response of Ca-bentonite (CB) amendment to improve the sewage sludge (SS) composting along with wheat straw (WS) as bulking agent. Five treatments (SS + WS) were mixed with or without blending of discrepant concentration of CB (2%, 4%, 6%, and 10%), respectively, and without CB added treatment applied as the control. The results showed that compared to control and 2%CB blended treatments, while the 6-10%CB -amended treatment indicated maximum enzymatic activities with the composting progress and highest organic matter degradation and loss. The amendment of 6-10%CB increased the humic acid, HA/FA ratio, DON, NH-N, NO and DOC but reduced the fulvic acids content and the maturity period by 2 weeks as compared to control. In addition, maturity parameters also confirmed that the highest seed germination was observed with the 10%CB applied compost followed by 6%CB, 4%CB and 2%CB applied treatments, respectively.
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http://dx.doi.org/10.1016/j.biortech.2018.04.023 | DOI Listing |
Adv Healthc Mater
September 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, College of Modern Chinese Medicine Industry, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by joint inflammation, damage, and disability. Activated fibroblast-like synoviocytes (FLSs), abundant in RA synovium, crucially facilitate disease progression. These activated FLSs drive RA pathogenesis by upregulating adhesion molecules, proinflammatory cytokines, chemokines, and major histocompatibility complex class II (MHC-II).
View Article and Find Full Text PDFMol Biotechnol
September 2025
Department of Biology, Faculty of Science, Marmara University, Göztepe, 34722, Istanbul, Türkiye.
Babesia bigemina, a tick-borne protozoan parasite, is one of the main causative agents of bovine babesiosis, a disease with significant economic impact on the cattle industry. One of the key enzymes involved in the parasite's metabolism is lactate dehydrogenase (LDH), which plays an essential role in the anaerobic glycolytic pathway by catalysing the conversion of pyruvate to lactate. In this study, B.
View Article and Find Full Text PDFAcc Chem Res
September 2025
Departamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, Ave. Ferrocarril San Rafael Atlixco 186, Col. Leyes de Reforma 1A sección, Alcaldía Iztapalapa, 09310 Mexico City, Mexico.
ConspectusWhat does the word antioxidant mean? Antioxidants are supposed to be nontoxic, versatile molecules capable of counteracting the damaging effects of oxidative stress (OS). Thus, when evaluating a candidate molecule as an antioxidant, several aspects should be considered. Antioxidants are more than free radical scavengers.
View Article and Find Full Text PDFLife Sci Alliance
December 2025
Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA
Nε-lysine acetylation in the lumen of the ER requires two acetyltransferases, ATase1/NAT8B and ATase2/NAT8. They are type II membrane proteins and belong to the larger GNAT superfamily of acetyltransferases. Their enzymatic activity is tightly coupled to the import of acetyl-CoA in the lumen of the ER by AT-1/SLC33A1.
View Article and Find Full Text PDFArch Biochem Biophys
September 2025
Department of Chemistry and Biochemistry, Howard College of Arts and Sciences, Samford University, 800 Lakeshore Drive, Birmingham, AL, USA, 35229. Electronic address:
Tetrahydrodipicolinate N-succinyltransferase (DapD) catalyzes the reaction of tetrahydrodipicolinate (THDP) and succinyl-CoA to form (S)-2-(3-carboxypropanamido)-6-oxoheptanedioic acid and coenzyme A. The enzyme is in the diaminopimelate-lysine biosynthesis pathway which produces two metabolites necessary for the survival and growth of pathogenic bacteria. Since lysine is an essential amino acid to humans, DapD is a potentially safe target for antibiotic therapies.
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