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Inertial microfluidics is an active field of research that deals with crossflow positioning of the suspended entities in microflows. Until now, the majority of the studies have focused on the behavior of rigid particles in order to provide guidelines for microfluidic applications such as sorting and filtering. Deformable entities such as bubbles and droplets are considered in fewer studies despite their importance in multiphase microflows. In this paper, we show that the trajectory of bubbles flowing in rectangular and square microchannels can be controlled by tuning the balance of forces acting on them. A T-junction geometry is employed to introduce bubbles into a microchannel and analyze their lateral equilibrium position in a range of Reynolds (1 < Re < 40) and capillary numbers (0.1 < Ca < 1). We find that the Reynolds number (Re), the capillary number (Ca), the diameter of the bubble (D[combining macron]), and the aspect ratio of the channel are the influential parameters in this phenomenon. For instance, at high Re, the flow pushes the bubble towards the wall while large Ca or D[combining macron] moves the bubble towards the center. Moreover, in the shallow channels, having aspect ratios higher than one, the bubble moves towards the narrower sidewalls. One important outcome of this study is that the equilibrium position of bubbles in rectangular channels is different from that of solid particles. The experimental observations are in good agreement with the performed numerical simulations and provide insights into the dynamics of bubbles in laminar flows which can be utilized in the design of flow based multiphase flow reactors.
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http://dx.doi.org/10.1039/c7lc01283g | DOI Listing |
Sci Rep
September 2025
Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia.
Synechococcus HS-9 is being recognized as one of the potential strains for biodiesel production due to its high levels of fatty acid methyl ester (FAME), which are around 70-78%. The first stage in producing microalgae biodiesel involves the biomass production process through a photobioreactor cultivation process. In addition to microalgae strains, the optimization of the photobioreactor's performance is essential for producing high biomass.
View Article and Find Full Text PDFUltrason Sonochem
August 2025
Donghai Laboratory, Zhoushan 316021, China; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China. Electronic address:
Hydrodynamic cavitation offers a promising technological platform for diverse industrial applications, including water treatment and chemical process intensification, and holds significant potential for widespread adoption in future advanced processing systems. This study investigates the disinfection efficacy of a novel Cylindrical Rotational Hydrodynamic Cavitation Reactor (CRHCR) and elucidates the underlying mechanism of Escherichia coli (E. coli) inactivation induced by hydrodynamic cavitation.
View Article and Find Full Text PDFUrolithiasis
March 2025
Department of Urology, University of Michigan, 4432 Medical Science I, 1301 Catherine Street, Ann Arbor, MI, 48109-5330, USA.
Stone ablation using the thulium fiber laser (TFL) at different pulse duration/peak power or laser fiber-to-stone distances requires further research to understand effective and safe settings. In this study we characterized the vapor bubble anatomy and stone crater morphology at various settings and standoff distances. Optical profiles of 1 J short pulse (SP), 1 J long pulse (LP), 3 J SP, and 2.
View Article and Find Full Text PDFPLoS One
May 2025
Department of Bioengineering Technologies, Applied Stem Cell Technologies Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Engineered heart tissues (EHTs) have shown great potential in recapitulating tissue organization, functions, and cell-cell interactions of the human heart in vitro. Currently, multiple EHT platforms are used by both industry and academia for different applications, such as drug discovery, disease modelling, and fundamental research. The tissues' contractile force, one of the main hallmarks of tissue function and maturation level of cardiomyocytes, can be read out from EHT platforms by optically tracking the movement of elastic pillars induced by the contractile tissues.
View Article and Find Full Text PDFUltrason Sonochem
January 2025
School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China; Tianjin Key Laboratory of Chemical process safety and equipment technology, Tianjin 300350, China. Electronic address:
Ultrasonic reactors, widely applied in process intensification, face limitations in their industrial application due to a lack of theoretical support for their structural design and optimization, particularly concerning the uniformity of the cavitation zone. Addressing this gap, our study introduces a novel approach to design a multi-frequency octagonal ultrasonic reactor of capacity 9.5 L through numerical simulation and spectrum analysis.
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