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Introduction: The aim of our study was to compare the reliability and safety of the classical I-AT with the continuous positive airway pressure apnea test (CPAP-AT).
Material And Methods: In the group of 48 patients (group O), an I-AT was performed at the end of BD diagnostic procedures, and approximately 1-1.5h later CPAP-AT with 100% FiO and CPAP of 10cm HO, provided by ventilator in CPAP mode. After pre‑oxygenation with 100% FiO for 10min, the PaO/FiO ratio was recorded prior to I-AT at time-point one (T1) and prior to CPAP-AT at time-point two (T2). Group O was categorized into subgroup N-H (non-hypoxemic), consisting of 41 patients with good lung function, and subgroup H (hypoxemic) consisting of 7 patients with poor lung function. Within each subgroup PaO/FiO at T1 and T2 were compared.
Results: In Group O, PaO/FiO decreased from 321±128mmHg at T1 to 291±119mmHg at T2 (p=0.004). In subgroup N-H, PaO/FiO declined from 355±103 to 321±100mmHg (p=0.008), and in subgroup H, PaO/FiO remained almost unchanged. Additionally, in 4 patients from subgroup N-H, PaO/FiO decreased below 200mmHg at T2.
Conclusions: Our study indicates that I-AT may compromise pulmonary function and this may support the recommendation of safer CPAP-AT alternative.
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http://dx.doi.org/10.1016/j.jcrc.2017.10.038 | DOI Listing |
Cureus
August 2025
Pharmacy Practice, Balaji Institute of Pharmaceutical Sciences, Warangal, IND.
Introduction: Smoking induces oxidative stress and inflammation, which can impair insulin function and increase the risk of developing diabetes. Understanding this modifiable risk factor across diverse demographic and socioeconomic groups is essential for targeted public health interventions.
Aims: To assess the relationship between current smoking and self-reported diabetes and to analyze how this association varies across demographics and socioeconomic characteristics.
AJNR Am J Neuroradiol
July 2025
From the Department of Radiology (A.F.J., L.V.R.), Center for Clinical Research, Biostatistics (N.H.), and Department of Otolaryngology-Head and Neck Surgery (A.H.E.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA; Department of Radiology (P.K.N.), Massachusetts Gener
Background And Purpose: Although the otic capsule is fully formed at birth, the vestibular aqueduct (VA) continues to mature postnatally. Failure of this maturation-VA hypoplasia-identifies a subgroup of Menière's disease (MD) patients and can be detected on CT by measuring the VA's angular trajectory (ATVA). However, the age at which ATVA stabilizes and hypoplasia can be reliably diagnosed remains unclear.
View Article and Find Full Text PDFSleep Breath
July 2025
Department of Occupational Health, Sleep Medicine Center and ENT, West China School of Public Health and West China Forth Hospital, Sichuan University, No.18, Section 3, Renmin South Road, Wuhou District, Chengdu, 610041, Sichuan Province, China.
Purpose: Few articles focus on the effect of CPAP on the nocturnal blood pressure in OSA patients. This study aims to evaluate the effects of continuous positive airway pressure (CPAP) therapy on nocturnal blood pressure in individuals with obstructive sleep apnea-hypopnea syndrome (OSAHS), which fills the research gap. Additionally, differences in nocturnal blood pressure measurements before and after CPAP therapy were analyzed across varying disease severities.
View Article and Find Full Text PDFBiosci Microbiota Food Health
February 2025
Corporate Planning Department, Yakult Honsha Co., Ltd., 1-10-30 Kaigan, Minato-ku, Tokyo 105-8660, Japan.
Older individuals with care needs and lower body mass indices (BMIs) are more likely to be malnourished. Unintentional weight loss, an indicator of malnutrition, significantly impacts the physical function and poor prognosis of older adults. This study aimed to explore the effects of long-term consumption of strain Shirota-fermented milk (LcFM) on body weight in the oldest old among nursing-home residents.
View Article and Find Full Text PDFEye Contact Lens
July 2025
Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, (P.K.M., A.B., S.S.P., N.H., R.S., T.A., N.S., J.S.T.), New Delhi, Delhi, India; and (S.M.), LVPEI, Bhubaneswar, India.
Purpose: Microbial keratitis accounts for significant proportion of corneal blindness. To know the underlying etiological micro-organism, performing corneal scraping is important for initiating the correct antibiotic therapy. A study was conducted to compare the efficacy and safety of 26-gauge needle and Kimura spatula for the same.
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