Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Building models of a biological system that are consistent with the myriad data available is one of the key challenges in biology. Modeling the structure and dynamics of macromolecular assemblies, for example, can give insights into how biological systems work, evolved, might be controlled, and even designed. Integrative structure modeling casts the building of structural models as a computational optimization problem, for which information about the assembly is encoded into a scoring function that evaluates candidate models. Here, we describe our open source software suite for integrative structure modeling, Integrative Modeling Platform (https://integrativemodeling.org), and demonstrate its use.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734277 | PMC |
| http://dx.doi.org/10.1002/pro.3311 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integrating opinion dynamics and differential game modeling for sustainable groundwater management.
Water Res
September 2025
College of Hydrology and Water Resources, Hohai University, Nanjing 210098, China. Electronic address:
Groundwater overextraction presents persistent challenges due to strategic interdependence among decentralized users. While game-theoretic models have advanced the analysis of individual incentives and collective outcomes, most frameworks assume fully rational agents and neglect the role of cognitive and social factors. This study proposes a coupled model that integrates opinion dynamics with a differential game of groundwater extraction, capturing the interaction between institutional authority and evolving stakeholder preferences.
View Article and Find Full Text PDFExploring the olfactory repertoire of the ecologically important parasitoid wasp Microplitis mediator (Hymenoptera: Braconidae): from gene structures to expression analysis.
J Econ Entomol
September 2025
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
The ability of parasitoid wasps to precisely locate hosts in complex environments is a key factor in suppressing pest populations. Chemical communication plays an essential role in mediating insect behaviors such as locating food sources, hosts, and mates. Odorant receptors (ORs) are the key connection between external odors and olfactory nerves.
View Article and Find Full Text PDFExploring Online Health Information-Seeking Behavior Among Young Adults: Scoping Review.
J Med Internet Res
September 2025
Department of Community Medicine, Faculty of Health, UiT The Arctic University of Norway, Tromsø, Norway.
Background: The ability to access and evaluate online health information is essential for young adults to manage their physical and mental well-being. With the growing integration of the internet, mobile technology, and social media, young adults (aged 18-30 years) are increasingly turning to digital platforms for health-related content. Despite this trend, there remains a lack of systematic insights into their specific behaviors, preferences, and needs when seeking health information online.
View Article and Find Full Text PDFUnderstanding the Behavioral Determinants of First Responder App Adoption by Integrating Perspectives From the Unified Theory of Acceptance and Use of Technology and Health Belief Model: Cross-Sectional Survey.
JMIR Hum Factors
September 2025
Media Psychology Lab, Department of Communication Science, KU Leuven, Leuven, Belgium.
Background: Out-of-hospital cardiac arrests (OHCAs) are a leading cause of death worldwide, yet first responder apps can significantly improve outcomes by mobilizing citizens to perform cardiopulmonary resuscitation before professional help arrives. Despite their importance, limited research has examined the psychological and behavioral factors that influence individuals' willingness to adopt these apps.
Objective: Given that first responder app use involves elements of both technology adoption and preventive health behavior, it is essential to examine this behavior from multiple theoretical perspectives.
Ultrahigh Sensitive Human Inspired Neurons for Artificial Nociceptor Systems.
ACS Nano
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan 523808, China.
Mimicking human brain functionalities with neuromorphic devices represents a pivotal breakthrough in developing bioinspired electronic systems. The human somatosensory system provides critical environmental information and facilitates responses to harmful stimuli, endowing us with good adaptive capabilities. However, current sensing technologies often struggle with insufficient sensitivity, dynamic response, and integration challenges.
View Article and Find Full Text PDF