Spontaneous and efficient adsorption of lysozyme from aqueous solutions by naturally polyanion gel beads.

Mater Sci Eng C Mater Biol Appl

MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.

Published: July 2017


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Article Abstract

In this study, polyanionic alginate gel beads crosslinked by Ca and glutaraldehyde have demonstrated a strong electrostatic interaction with specific proteins. Due to the naturally abundant carboxyl groups, the prepared alginate gel beads exhibited a relatively superior integrated adsorption performance toward lysozyme, including a superior adsorption capacity of 213mgg, fast adsorption equilibrium within 12h, good selectivity, and good reversibility. Compared with other protein adsorbents, the as-prepared adsorptive beads have the advantages of excellent adsorption performance, easy to prepare, convenient, efficient, reliable and environment-friendly to apply, which can serve as a more sustainable material in protein separation and purification.

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http://dx.doi.org/10.1016/j.msec.2017.03.092DOI Listing

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