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Objective: To investigate efficacy and safety of phaco-trabectome (PT) versus phaco-iStent (Pi) for intraocular pressure (IOP) control in open-angle glaucoma (OAG).
Design: Retrospective comparative case series.
Participants: A total of 70 eyes of 55 patients with OAG underwent either PT surgery by a single surgeon or Pi (insertion of 2 stents) by another surgeon in Canada between January 2010 and December 2012.
Methods: The medical records of consecutive adult patients who underwent either PT or Pi surgery were reviewed. All patients who satisfied both the inclusion and exclusion criteria were included in the outcomes analyses. IOP reduction, reduction in glaucoma medication, safety profile, and best-corrected visual acuity were evaluated.
Results: Thirty-six eyes of 30 patients had PT and 34 eyes of 25 patients had Pi. Baseline IOP was higher in the PT group (20.92 ± 5.07 mm Hg) than in the Pi group (17.47 ± 4.87 mm Hg; p = 0.026). At 12 months there was no significant difference between groups in relative reduction of mean IOP (PT -5.09 ± 5.73, 24% relative reduction vs. Pi -3.84 ± 3.80, 22% relative reduction; p = 0.331) or glaucoma medication use (PT -0.49 ± 1.17 vs. Pi -0.26 ± 0.73; p = 0.168) from baseline. However, Pi had significantly fewer individual complications (PT 20 vs. Pi 5; p < 0.0001) throughout the postoperative period.
Conclusion: At 12 months of follow-up, both techniques significantly lowered IOP, but fewer complications were observed in the Pi group.
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http://dx.doi.org/10.1016/j.jcjo.2016.06.018 | DOI Listing |
Ocul Immunol Inflamm
September 2025
National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
Purpose: To report pyramidal-like, hyperreflective changes of the outer retina and retinal pigmented epithelium (RPE) in three patients with an atypical non-syphilitic outer retinopathy.
Study Design/materials And Methods: Single institutional case series conducted at the National Eye Institute, National Institutes of Health.
Results: Hyperreflective, pyramidal lesions of the outer retina and RPE have been described in patients with syphilitic posterior segment uveitis.
Objective: To evaluate the measurement accuracy of 2 swept-source optical biometers, the IOLMaster 700 and the Revo FC 130, in patients diagnosed with cataracts.
Methods: We conducted a prospective, observational and comparative study in patients older than 40 years with cataracts. A single operator performed optical biometry using both devices during the same session.
Am J Ophthalmol
September 2025
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Topic: The aim of this systematic review and meta-analysis is to evaluate best-corrected visual acuity (VA) outcomes following transscleral cyclophotocoagulation (TSCPC) in patients with refractory glaucoma.
Clinical Relevance: TSCPC is typically reserved for cases of refractory glaucoma, due to apprehension of negative affects on VA. Prior studies have reported the VA outcomes from TSCPC, but no comprehensive review of the literature has yet been conducted.
Am J Ophthalmol
September 2025
Department of Ophthalmology, Université de Montréal, Montréal, Québec, Canada.
Purpose: To evaluate the incidence, risk factors, management strategies, and visual outcomes of retinal detachment (RD) following Boston Keratoprosthesis Type 1 (KPro) implantation.
Design: Single-center, retrospective observational case series.
Methods: Medical records of 157 eyes from 122 adult patients who underwent Boston Type 1 KPro implantation at a tertiary care center between 2008 and 2022 were reviewed.
Int J Radiat Oncol Biol Phys
September 2025
Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital and the University of Hong Kong, China.
Title: Can Radiotherapy Quality Assurance (RT QA) improve nasopharyngeal cancer (NPC) outcomes in low- and middle-income countries (LMICs) -Reporting phase 2 of a prospective International Atomic Energy Agency (IAEA) study (E33039).
Background: Most of new NPC cases occur in LMICs, but these patients experience poorer survival than new NPC cases in high income countries. This study seeks to determine whether a radiotherapy quality assurance (RT QA) programme can improve NPC patient outcomes in LMICs.