Publications by authors named "Christopher J Rudnisky"

Objective: To assess the effectiveness of intracameral lidocaine during routine cataract surgery.

Design: Prospective, single-blinded, randomized, controlled trial.

Participants: Adult patients undergoing routine phacoemulsification cataract extraction in a chartered surgical facility in Edmonton, Alberta, Canada, were enrolled in the study.

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Objective: To investigate and assess the intraoperative predictors for successful 1-year outcomes of iStent inject for patients with open angle glaucoma.

Design: Retrospective case series.

Participants: Patients who underwent combined iStent inject placement and cataract surgery between October 2018 and August 2022.

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To evaluate the effect of antivascular endothelial growth factor (anti-VEGF)-related endophthalmitis on intravitreal injection (IVI) frequency in patients with neovascular age-related macular degeneration (nAMD). A retrospective chart review was performed of all cases of post IVI endophthalmitis that occurred in Edmonton, Alberta, Canada, between 2012 and 2019. Contralateral eyes affected by nAMD but without endophthalmitis served as a control group.

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Purpose: To develop evidence-based milestones for cataract surgery teaching and identify performance indicators.

Setting: Royal Alexandra Hospital, Edmonton, Alberta, Canada.

Design: Retrospective cohort study.

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Objective: To describe the steps, hurdles, and recommendations for implementation of the immediately sequential bilateral cataract surgery (ISBCS) evidence-based protocol at a high-volume Canadian tertiary care centre.

Design: Quality-improvement study.

Participants: A total of 406 patients who underwent ISBCS from July 2020 to December 2020.

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Precis: A teleglaucoma (TG) case-finding model was used in Kenya. Of the patients, 3.46% had definite glaucoma and 4.

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Iatrogenic ocular injuries from unexpected cannula ejection during ophthalmic surgery are rare and can cause vision-threatening damage. This report describes 2 cases of cannula-associated ocular injuries that resulted in good visual outcome, despite the cannula traveling intrastromally through the visual axis.

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Purpose: This article identifies clinical features that differentiate central serous chorioretinopathy (CSR) from neovascular age-related macular degeneration (nAMD) and uses this information to develop a diagnostic tool.

Methods: A prospective observational study was conducted of patients with a new diagnosis of CSR, nAMD, or indeterminate presentation. All patients underwent clinical assessment, axial length measurement, enhanced-depth imaging-optical coherence tomography, and intravenous fluorescein angiography.

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Objective: To report the effect of hydroxychloroquine therapy cessation on the multifocal electroretinogram (mfERG) in a case series of patients with rheumatic disease suspected to have retinopathy.

Methods: Comprehensive data were retrospectively reviewed on 14 patients from a total of 50 cases who discontinued hydroxychloroquine due to suspected toxicity. Patients were followed for 4 years after the cessation of therapy.

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Objective: To evaluate preoperative testing for cataract surgery, implement stakeholder-driven change, and increase the number of patients who arrived for surgery with complete preoperative requirements, for the purpose of delivering safe, high-quality, and cost-effective care for patients.

Design: Quality improvement.

Participants: Cataract surgery patients, health care staff in Ophthalmology Day Surgery, an Ophthalmology improvement team, the Clinical Section Heads of Ophthalmology and Anaesthesia, Quality Consultants, and members of the Quality Council participated in this study.

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Objective: To compare the efficacy and safety of ab interno trabeculectomy with the Trabectome combined with cataract surgery (phaco-AIT) versus Trabeculectomy with mitomycin C combined with cataract surgery (phaco-Trab) in open-angle glaucoma.

Methods: A prospective randomized controlled trial with a single surgeon and surgical center was undertaken. Patients were recruited from July 2009 to October 2014.

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Objective: To investigate the visual and anatomical outcomes of Boston keratoprosthesis (Kpro) type 1 reimplantation.

Design: Subgroup analysis of multicentre prospective cohort study.

Participants: Of 303 eyes that underwent Kpro implantation between January 2003 and July 2008 by 1 of 19 surgeons at 18 medical centres, 13 eyes of 13 patients who underwent reimplantation of Boston Kpro type 1 were compared with 13 eyes of 13 diagnosis-matched patients who underwent initial implantation.

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Background: Current practice methods are unclear as to the most safe and effective prophylactic pharmacotherapy and method of delivery to reduce postoperative endophthalmitis occurrence.

Methods: A systematic review and meta-analysis using Meta-analysis of Observational Studies in Epidemiology guidelines was performed to compare the efficacy of intracameral cefuroxime, moxifloxacin and vancomycin in preventing postphacoemulsification cataract surgery endophthalmitis. A safety analysis of intracameral antibiotics was concurrently performed.

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Purpose: To study the prognostic factors and clinical outcomes of patients who underwent pars plana vitrectomy, subretinal injection of tissue plasminogen activator, and gas tamponade for the treatment of subfoveal hemorrhage (SFH).

Methods: A retrospective noncomparative interventional case series.

Results: Seventy-eight eyes from 77 patients were included.

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Objective: The Screening for Limb, I-Eye, Cardiovascular, and Kidney Complications (SLICK) Program was implemented in 1999 to improve diabetic care for Alberta First Nations individuals living on reserve. The purpose of this review is to determine the rate and predictors of progression of diabetic retinopathy (DR) over a 10-year period.

Design: Cohort study.

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Purpose: To determine the rate of retinal tear and retinal detachment (RD) after neodymium:YAG (Nd:YAG) laser capsulotomy for posterior capsule opacification (PCO) after cataract surgery.

Setting: Province-wide outpatient and hospital settings, Alberta, Canada.

Design: Database study.

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Objective: To investigate efficacy and safety of phaco-trabectome (PT) versus phaco-iStent (Pi) for intraocular pressure (IOP) control in open-angle glaucoma (OAG).

Design: Retrospective comparative case series.

Participants: A total of 70 eyes of 55 patients with OAG underwent either PT surgery by a single surgeon or Pi (insertion of 2 stents) by another surgeon in Canada between January 2010 and December 2012.

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We introduce new binocular accuracy measures as alternatives to conventional marginal measures that can be used to evaluate screening tests in diagnostic studies involving paired organs (e.g. eyes and ears).

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Purpose: To report logarithm of the minimal angle of resolution (logMAR) visual outcomes of the Boston keratoprosthesis type 1.

Design: Prospective cohort study.

Methods: Preoperative, intraoperative, and postoperative parameters of 300 eyes of 300 patients who underwent implantation of a Boston keratoprosthesis type 1 device between January 2003 and July 2008 by 1 of 19 surgeons at 18 medical centers were collected.

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We present a model for describing correlated binocular data from reader-based diagnostic studies, where the same group of readers evaluates the presence or absence of certain diseases on binocular organs (e.g., fellow eyes) of patients.

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Objective: To determine the relationship between cataract severity and socioeconomic status (SES).

Design: Retrospective, observational case series. A total of 1350 eyes underwent phacoemulsification cataract extraction by a single surgeon using an Alcon Infiniti system.

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Purpose: To evaluate the efficacy of pars plana vitrectomy for congenital optic disk pit maculopathy with various adjuvant techniques, including gas tamponade, internal limiting membrane peel, and temporal optic disk endolaser in a multicenter study with long-term follow-up.

Methods: A retrospective chart review was performed to identify eyes that underwent surgical repair for congenital optic disk pits and serous macular detachment with or without macular retinoschisis from four retinal centers across Canada from 2003 to 2013. Data collected included surgeries performed, preoperative and postoperative vision, central retinal thickness, and presence or absence of subretinal fluid.

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Exposure to ionizing radiation, such as that used in fluoroscopy, can lead to cataracts. This is relevant in orthopedic surgery as fluoroscopic procedures are commonly performed. In this study, we determined perceived level of: (1) personal risk, (2) awareness of risk for cataract formation due to ionizing radiation exposure, (3) awareness of occupational dose limits for ophthalmologic radiation exposure, (4) current radioprotective practices amongst orthopedic surgeons.

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