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Objective: To investigate and assess the intraoperative predictors for successful 1-year outcomes of iStent inject for patients with open angle glaucoma.
Design: Retrospective case series.
Participants: Patients who underwent combined iStent inject placement and cataract surgery between October 2018 and August 2022.
Methods: A priori predictors of interest included the number of stents placed, the number of clicks required to place them, stent spacing, intraoperative reflux of blood from the stent, and observed flow of aqueous through external vasculature. The primary outcome was the intraocular pressure (IOP) medication index.
Results: This study included 99 eyes of 57 patients. The mean preoperative IOP was 14.9 (±3.7) mm Hg, and mean number of drops were 1.7 (±0.7). The mean postoperative follow-up was 15.6 (±5.9) months. The mean postoperative IOP was 13.6 (±6.1) mm Hg and medication reduction was -1.5 (±4.2 mm Hg). Using the IOP medication index, 92.6% of eyes were categorized as having a successful procedure. Multivariate analysis showed that flow in both one (p = 0.030) and two (p = 0.034) stents were independent predictors of success after 1 year.
Conclusions: The IOP medication index showed a statistically significant association between flow from both 1 and 2 stents. Flow can be used as a predictor by surgeons to change patients' surgical plans intraoperatively and to monitor patients more closely postoperatively.
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http://dx.doi.org/10.1016/j.jcjo.2025.06.007 | DOI Listing |
J Glaucoma
September 2025
Department of Ophthalmology, University of Campinas, Campinas, São Paulo, Brazil.
Prcis: Gonioscopy-Assisted Transluminal Trabeculotomy achieved a higher success rate than Bent Ab interno Needle Goniotomy in pseudophakic primary open angle glaucoma eyes at 12-months.
Purpose: To evaluate and compare efficacy and safety of standalone Bent Ab interno Needle Goniotomy (BANG) and Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in pseudophakic primary open angle glaucoma (POAG) eyes.
Methods: Parallel, double-arm, 1:1 ratio, single masked, single surgeon, randomized clinical trial.
Clin Exp Ophthalmol
September 2025
Department of Neurosurgery, National Neuroscience Institute, Singapore, Singapore.
Background: To describe clinical features, risk factors and outcomes of out-of-the-bag (OTB) intraocular lens (IOL) dislocation in dead bag syndrome (DBS).
Methods: Retrospective review of a single-surgeon series of eyes with IOLs that developed OTB IOL dislocation, managed at Singapore National Eye Centre (January 2014-December 2021), with a minimum of 6 months of follow-up. Eyes with OTB IOL dislocation following secondary IOL implantation and intraoperative capsule complications were excluded.
Zhonghua Yan Ke Za Zhi
September 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.
The rise of minimally invasive glaucoma surgery (MIGS) has brought new options to glaucoma treatment. However, there are significant differences between MIGS and traditional trabeculectomy in terms of surgical philosophy, applicable populations, and long-term efficacy. As a classic procedure, trabeculectomy achieves a well-documented intraocular pressure (IOP)-lowering effect but is associated with a higher risk of complications.
View Article and Find Full Text PDFAm J Ophthalmol Case Rep
September 2025
Columbia University Medical Center, Norwalk, Connecticut, USA.
Purpose: To report a surgical treatment for neovascular angle closure glaucoma.
Observations: A 69 year-old man with proliferative diabetic retinopathy developed neovascular angle closure with intraocular pressure (IOP) 60 mm Hg. Surgical goniosynechialysis and placement of a Hydrus canalicular stent were combined with pupilloplasty using an iris cerclage suture to maintain tension on the peripheral iris to limit reformation of goniosynechiae.