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Surface modification techniques have been developed significantly in the last couple of decades for enhanced tribological performance of artificial hip implants. Surface modification techniques improve biological, chemical and mechanical properties of implant surfaces. Some of the most effective techniques, namely surface texturing, surface coating, and surface grafting, are applied to reduce the friction and wear of artificial implants. This article reviews the status of the developments of surface modification techniques and their effects on commonly used artificial joint implants. This study focused only on artificial hip joint prostheses research of the last 10 years. A total of 27 articles were critically reviewed and categorized according to surface modification technique. The literature reveals that modified surfaces exhibit reduced friction and enhanced wear resistance of the contact surfaces. However, the wear rates are still noticeable in case of surface texturing and surface coating. The associated vortex flow aids to release entrapped wear debris and thus increase the wear particles generation in case of textured surfaces. The earlier delamination of coating materials due to poor adhesion and graphitization transformation has limited the use of coating techniques. Moreover, the produced wear debris has adverse effects on biological fluid. Conversely, the surface grafting technique provides phospholipid like layer that exhibited lower friction and almost zero wear rates even after a longer period of friction and wear test. The findings suggest that further investigations are required to identify the role of surface grafting on film formation and heat resistance ability under physiological hip joint conditions for improved performance and longevity of hip implants.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278906 | PMC |
http://dx.doi.org/10.1080/14686996.2016.1240575 | DOI Listing |
Environ Res
September 2025
State Key Laboratory for Ecological Security of Regions and Cities, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China. Electronic address:
Recent interest in amendments derived from industrial by-products has highlighted their potential for both resource recycling and heavy metal remediation. Phosphate tailings (PT), primarily dolomite-based solid waste with low utilization rates, offer a promising yet underexplored solution. This study pioneers the thermal modification of PT into a novel amendment, thermally modified phosphate tailings (TPT), to assess its adsorption performance, underlying mechanisms, and effectiveness in immobilizing heavy metals in soils.
View Article and Find Full Text PDFBiomed Mater
September 2025
Lanzhou University Second Hospital, No.82 Cuiyingmen Street, Lanzhou, Lanzhou, Gansu, 730030, CHINA.
In recent years, the incidence of orthopedic diseases has increased significantly, while traditional treatments often face limitations such as limited efficacy and pronounced side effects. The development of nanomedicine technology provides novel strategies for orthopedic disease treatment. As an emerging two-dimensional (2D) nanomaterial, black phosphorus nanosheets (BPNS) demonstrate remarkable potential in treating orthopedic diseases due to their unique physicochemical properties, superior biocompatibility, and the fact that their degradation product-elemental phosphorus-constitutes an essential component of bone tissue.
View Article and Find Full Text PDFCell Rep Med
September 2025
Translational Research Unit, Department of Cellular Therapy, Oslo University Hospital, Sognsvannsveien 20, 0372 Oslo, Norway. Electronic address:
Accurate identification of tumor-specific markers is vital for developing chimeric antigen receptor (CAR)-based therapies. While cell surface antigens are seldom cancer-restricted, their post-translational modifications (PTMs), particularly aberrant carbohydrate structures, offer attractive alternatives. Among these, the sialyl-Tn (STn) antigen stands out for its prevalent presence in various epithelial tumors.
View Article and Find Full Text PDFBiomater Adv
September 2025
Graduate School of Medical and Dental Science, Institute of Science Tokyo, 15-45 Yushima, Bunkyo, Tokyo, 113-8510, Japan; Advanced Central Research Organization, Teikyo University, 2-11-1, Kaga, Itabashi, Tokyo, 173-8605, Japan.
This review concentrates on the electroactive ceramic biointerfaces inspired by bone piezoelectricity for advanced ceramic biomaterials. Bone generates electrical potentials through the piezoelectric properties of collagen fibrils and apatite minerals under mechanical loading. These electrical signals influence osteoconductivity and regenerative capacity by osteogenic cells.
View Article and Find Full Text PDFACS Biomater Sci Eng
September 2025
Materials Engineering, McGill university, Montreal H3A0C5, Canada.
Transcutaneous devices such as dental implants frequently fail due to infections at their interfaces with epithelial tissues. These infections are facilitated by the lack of integration between the devices and the surrounding soft tissues. This study aims to improve epithelial integration through surface modification of a transcutaneous implant material (polyetheretherketone (PEEK)).
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