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This article gives a formal definition of a lognormal family of probability distributions on the set of symmetric positive definite (SPD) matrices, seen as a matrix-variate extension of the univariate lognormal family of distributions. Two forms of this distribution are obtained as the large sample limiting distribution via the central limit theorem of two types of geometric averages of i.i.d. SPD matrices: the log-Euclidean average and the canonical geometric average. These averages correspond to two different geometries imposed on the set of SPD matrices. The limiting distributions of these averages are used to provide large-sample confidence regions and two-sample tests for the corresponding population means. The methods are illustrated on a voxelwise analysis of diffusion tensor imaging data, permitting a comparison between the various average types from the point of view of their sampling variability.
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http://dx.doi.org/10.1111/insr.12113 | DOI Listing |
IEEE Trans Neural Netw Learn Syst
August 2025
Symmetric positive definite (SPD) matrices have been widely used as Riemannian feature descriptors in various scientific fields, due to their capacity to encode effective manifold-valued representations. Inspired by the architectural principles of Euclidean deep learning, the emerging SPD neural networks have achieved more robust signal classification. Among these advancements, Riemannian batch normalization (RBN) based on the affine-invariant Riemannian metric (AIRM) has emerged as a key technique for enhancing the learning capability of SPD-based networks.
View Article and Find Full Text PDFHum Brain Mapp
August 2025
School of Information Technology, Monash University, Subang Jaya, Malaysia.
Common measures of brain functional connectivity (FC) including covariance and correlation matrices are symmetry-positive definite (SPD) matrices residing on a cone-shaped Riemannian manifold. Despite its remarkable success for Euclidean-valued data generation, the use of standard generative adversarial networks (GANs) to generate manifold-valued FC data neglects its inherent SPD structure and hence the inter-relatedness of edges in real FC. We propose a novel graph-regularized manifold-aware conditional Wasserstein GAN (GR-SPD-GAN) for FC data generation on the SPD manifold that can preserve the global FC structure.
View Article and Find Full Text PDFJ Neural Eng
July 2025
Systems Research Institute, Polish Academy of Science, 01-447 Warsaw, Poland.
. Electroencephalography (EEG) signals can reflect motor intention signals in the brain. In recent years, motor imagery (MI) based brain-computer interfaces (BCIs) have attracted the attention of neuroinformatics researchers.
View Article and Find Full Text PDFPLoS Comput Biol
May 2025
Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, United States of America.
The genome is organized into distinct chromatin compartments with at least two main classes, a transcriptionally active A and an inactive B compartment, broadly corresponding to euchromatin and heterochromatin. Chromatin regions within the same compartment preferentially interact with each other over regions in the opposite compartment. A/B compartments are traditionally identified from ensemble Hi-C contact frequency matrices using principal component analysis of their covariance matrices.
View Article and Find Full Text PDFNeuroimage
July 2025
MOE Frontier Science Center for Brain Science and Brain-machine Integration, Zhejiang University, Hangzhou, China; Nanhu Brain-computer Interface Institute, Hangzhou, China; School of Computer Science and Technology, Zhejiang University, Hangzhou, China; State Key Laboratory of Brain-machine Intelli
Modeling brain functional connectivity (FC) is key in investigating brain functions and dysfunctions. FC is typically quantified by symmetric positive definite (SPD) matrices that are located on a Riemannian manifold rather than the regular Euclidean space, whose modeling faces three challenges. First, FC can be time-varying and the temporal dynamics of FC matrix time-series need to be modeled within the constraint of the SPD Riemannian manifold geometry, which remains elusive.
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