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Background: Sternoclavicular joint (SCJ) infectious arthritis is a rare disease. A standard treatment for SCJ infection has not been established. This study aimed to assess the clinical outcomes of a three-stage procedure with bone transportation (BT) for treating SCJ infectious arthritis.
Methods: Six patients (mean age 39.5 years) with chronic SCJ infectious arthritis were included in the study. The patients underwent a three-stage treatment between January 2009 and December 2012, and results were analyzed retrospectively. Following debridement, immediate flap closure was conducted, and BT of the clavicle was performed to fill the gap using a monolateral external fixator. SCJ reconstruction with a tendon autograft was performed, and the external fixator was finally removed. Clinical outcomes were evaluated using Disabilities of the Arm, Shoulder, and Hand (DASH) scores and Constant scores. The average follow-up period was 16 months (range 12-36 months).
Results: The DASH scores decreased from 53.6 ± 4.9 preoperatively to 24.4 ± 3.1 postoperatively. The Constant scores for pain, activity level, positioning, strength, and range of motion were significantly high after the treatment. The total Constant score improved from 32.5 ± 5.8 preoperatively to 76.7 ± 6.4 postoperatively. All patients were satisfied with the therapeutic effect. No complications occurred.
Conclusions: The three-stage procedure with BT improves shoulder function and movement and relieves pain. It is an effective and safe method for treating SCJ infectious arthritis.
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http://dx.doi.org/10.1186/s13018-016-0480-0 | DOI Listing |
Arthritis Rheumatol
September 2025
Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, 94305.
Can Vet J
September 2025
Faculté de Médecine Vétérinaire, Université de Montréal, 3200, rue Sicotte, Saint-Hyacinthe (Québec) J2S 2M2.
Debilitated calves are often presented with an umbilical remnant infection, septic arthritis, or both. These comorbidities, frequently caused by similar bacteria, must be addressed surgically. In cases of omphalophlebitis where the infection reaches the liver, the clinician generally has 1 option: marsupialization of the vein.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
MS4A4A belongs to the MS4A tetraspan protein superfamily and is selectively expressed by the monocyte-macrophage lineage. In this study, we aimed to evaluate the role of MS4A4A+ macrophages in rheumatoid arthritis (RA) pathogenesis and response to treatment. RNA sequencing and immunohistochemistry of synovial samples from either early treatment-naïve or active chronic RA patients showed that MS4A4A expression positively correlated with synovial inflammation.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Phase I Clinical Trial Research Ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of China.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an emerging global health concern, and its presence increases the risk of multi-system diseases. This study aimed to investigate the multimorbidity trajectories of chronic diseases in people living with MASLD.
Methods: We identified 137 859 MASLD patients in UK Biobank and used 'propensity score matching' to match an equal number of non-MASLD controls.
Int J Infect Dis
September 2025
Servicio de Brucellosis, Hospital F. J. Muñiz, 1282 Buenos Aires, Argentina.
Objectives: Brucellosis remains a significant zoonotic disease in endemic regions, with relapse and focal complications posing significant clinical challenges. This study aimed to identify risk factors associated with brucellosis relapse and focal disease in North Khorasan, Iran, over a nine-year period.
Methods: A retrospective analysis was conducted on 2,568 confirmed brucellosis cases from 2015 to 2024, using data from multiple centers.