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State-space reconstruction is investigated for evaluating the randomness generated by an optically injected semiconductor laser in chaos. The reconstruction of the attractor requires only the emission intensity time series, allowing both experimental and numerical evaluations with good qualitative agreement. The randomness generation is evaluated by the divergence of neighboring states, which is quantified by the time-dependent exponents (TDEs) as well as the associated entropies. Averaged over the entire attractor, the mean TDE is observed to be positive as it increases with the evolution time through chaotic mixing. At a constant laser noise strength, the mean TDE for chaos is observed to be greater than that for periodic dynamics, as attributed to the effect of noise amplification by chaos. After discretization, the Shannon entropies continually generated by the laser for the output bits are estimated in providing a fundamental basis for random bit generation, where a combined output bit rate reaching 200 Gb/s is illustrated using practical tests. Overall, based on the reconstructed states, the TDEs and entropies offer a direct experimental verification of the randomness generated in the chaotic laser.
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http://dx.doi.org/10.1103/PhysRevE.94.042214 | DOI Listing |
Sci Adv
September 2025
James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Narrow-linewidth lasers are essential for coherent optical applications, including communications, metrology, and sensing. Although compact semiconductor lasers with narrow linewidths have been demonstrated, achieving high spectral purity generally necessitates passive external cavities based on photonic integrated circuits. This study presents a theoretical and experimental demonstration of a monolithic optical injection locking topological interface state extended (MOIL-TISE) laser.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
September 2025
Center for Visual Science, University of Rochester, Rochester, NY, United States.
Purpose: Adaptive optics scanning light ophthalmoscopy (AOSLO) paired with intravitreal injection of a viral vector coding for the calcium indicator GCaMP has enabled visualization of neuronal activity in retinal ganglion cells (RGCs) at single cell resolution in the living eye. However, the inner limiting membrane (ILM) restricts viral transduction to the fovea in humans and non-human primates, hindering both therapeutic intervention and physiological study of the retina. To address this issue, we explored peeling the ILM before intravitreal injection to expand calcium imaging beyond the fovea in the living primate eye.
View Article and Find Full Text PDFSmall
September 2025
Physical Chemistry, TU Dresden, Zellescher Weg 19, 01069, Dresden, Germany.
III-V semiconductor nanocrystals (NCs) have emerged as a benign alternative to II-VI and IV-VI NCs, which are restricted due to the toxicity of the comprising elements. While InP NCs advanced significantly, the development of infrared-emitting InAs NCs has been relatively slow-paced. This is due to the synthetic challenges arising from the highly covalent bonding in InAs and the limited range of available arsenic sources.
View Article and Find Full Text PDFRetin Cases Brief Rep
October 2024
Eye Clinic, Humanitas-Gradenigo Hospital, Torino, Italy.
Purpose: To study the efficacy and safety of pro re nata regimen of brolucizumab, without loading dose, in treatment-naive patients with neovascular age-related macular degeneration (nAMD).
Case Series: Retrospective, observational study. We included all consecutive patients diagnosed with treatment- naïve nAMD undergoing Brolucizumab in Humanitas eye clinic, Turin, Italy between April 2022 and May 2023.
Retin Cases Brief Rep
September 2025
Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, University of California of Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Purpose: To describe a case of recalcitrant bilateral peripapillary pachychoroid syndrome (PPS) treated with high-dose (HD) intravitreal aflibercept injections.
Methods: Medical and imaging records were retrospectively evaluated. Multimodal imaging included ultra-widefield indocyanine green and fluorescein angiography and fundus autofluorescence.