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The authors investigated the relationship between the awareness of dietary salt and genetics and the intent to maintain a low-salt diet. In particular, they assessed whether hypothetical genetic information regarding salt-sensitive hypertension motivates the intent to reduce dietary salt for communicating the health benefits of lower salt consumption to citizens. A self-administered questionnaire survey was conducted with 2500 randomly sampled residents aged 30 to 69 years living in Nagahama, Japan. Genetic information regarding higher salt sensitivity increased motivation to reduce salt intake for both those who agreed that genes cause hypertension and those who did not. Less than 50% of those who agreed that genes cause hypertension lost their intention to lower their salt consumption when they found they did not possess the susceptibility gene. Communicating genetic information positively affected motivation to reduce salt intake. The present study clarifies the difficulty in changing the behavioral intent of those who have significantly less incentive to reduce salt intake. Therefore, a multidimensional approach is crucial to reduce salt consumption.
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http://dx.doi.org/10.1111/jch.12897 | DOI Listing |
Funct Integr Genomics
September 2025
Zhengzhou Research Base, State Key Laboratory of Cotton Bio-Breeding and Integrated Utilization, Zhengzhou University/Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Zhengzhou, China.
In this study, a comprehensive genome-wide identification and analysis of the aldo-keto reductase (AKR) gene family was performed to explore the role of Gossypium hirsutumAKR40 under salt stress in cotton. A total of 249 AKR genes were identified with uneven distribution on the chromosomes in four cotton species. The diversity and evolutionary relationship of the cotton AKR gene family was identified using physio-chemical analysis, phylogenetic tree construction, conserved motif analysis, chromosomal localization, prediction of cis-acting elements, and calculation of evolutionary selection pressure under 300 mM NaCl stress.
View Article and Find Full Text PDFDrug Dev Res
September 2025
School of Pharmacy, The University of Jordan, Amman, Jordan.
Cancer treatment faces challenges like nonselective toxicity and drug resistance, prompting the need for innovative therapies. This study aimed to develop liposomal formulations for co-delivery of empagliflozin and rutin, evaluating their anticancer and antioxidant efficacy. PEGylated empagliflozin-loaded nanoliposomes (Empa-NLs) and empagliflozin-rutin co-loaded nanoliposomes (Empa-Rut NLs) were synthesized using the thin-film hydration technique.
View Article and Find Full Text PDFJAMIA Open
October 2025
Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.
Objectives: Type 2 diabetes (T2D) is a growing public health burden with persistent racial and ethnic disparities. . This study assessed the completeness of social determinants of health (SdoH) data for patients with T2D in Epic Cosmos, a nationwide, cross-institutional electronic health recors (EHR) database.
View Article and Find Full Text PDFInt J Hypertens
August 2025
Health & Society Program, College of Arts & Sciences, University of Massachusetts Dartmouth, 285 Old Westport Rd, Dartmouth 02747, Massachusetts, USA.
The Dietary Approaches to Stop Hypertension (DASH) diet is an internationally recognized anti-hypertensive dietary model. This systematic scoping review examines the effectiveness of digital-based interventions utilizing the DASH dietary pattern. A search was conducted using 14 databases to include relevant studies from 1997 to January 2025 using PRISMA guidelines for scoping reviews.
View Article and Find Full Text PDFACS Omega
September 2025
Changsha Research Institute of Mining and Metallurgy CO., LTD, Changsha 410012, Hunan, China.
The long-term accumulation of electrolytic manganese residue leads to pollution issues related to NH -N and Mn. Although various methods exist to address the pollution caused by NH -N and Mn, existing hazard-free treatment methods do not consider the subsequent utilization of the electrolytic manganese residue. Meanwhile, resource recovery methods face challenges due to the complex salt structures present in electrolytic manganese residue.
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