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Article Abstract
Objective: We studied associations between pancreatic cancer and occupational exposures to metals, solvents, chemicals, and endotoxin in a cohort of female textile workers in Shanghai, China. To assess the longer-term influences of these agents on pancreatic cancer we extended follow-up of this previously studied cohort.
Methods: We utilized a job exposure matrix to assess occupational exposures for 481 pancreatic cancer cases and a randomly selected sub-cohort of 3191 non-cases. We calculated hazard ratios and 95% confidence intervals using Cox proportional hazards modeling adapted for the case-cohort design.
Results: We observed a statistically significant trend of increasing hazard ratios associated with solvent exposure, but no associations with any of the remaining occupational exposures, including endotoxin and metals.
Conclusions: Our findings of increasing risk of pancreatic cancer with solvent exposures are consistent with published literature.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870312 | PMC |
| http://dx.doi.org/10.1097/JOM.0000000000000596 | DOI Listing |
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