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Task-specific dystonia is a form of isolated focal dystonia with the peculiarity of being displayed only during performance of a specific skilled motor task. This distinctive feature makes task-specific dystonia a particularly mysterious and fascinating neurological condition. In this review, we cover phenomenology and its increasingly broad-spectrum risk factors for the disease, critically review pathophysiological theories and evaluate current therapeutic options. We conclude by highlighting the unique features of task-specific dystonia within the wider concept of dystonia. We emphasise the central contribution of environmental risk factors, and propose a model by which these triggers may impact on the motor control of skilled movement. By viewing task-specific dystonia through this new lens which considers the disorder a modifiable disorder of motor control, we are optimistic that research will yield novel therapeutic avenues for this highly motivated group of patients.
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http://dx.doi.org/10.1136/jnnp-2015-311298 | DOI Listing |
Tremor Other Hyperkinet Mov (N Y)
September 2025
Division of Neurology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.
Objective: To describe a unique form of task-specific tremor (TST) in billiards players.
Background: Task-specific movement disorders occur during highly learned activities. While task-specific dystonia in billiards players has been reported, TST has not been previously characterized.
Mov Disord Clin Pract
September 2025
Department of Neurology, Ramaiah Medical College and Hospitals, Ramaiah University of Applied Sciences, Bengaluru, India.
Background: Chewing dystonia is a rare, task-specific oromandibular dystonia that causes involuntary jaw and tongue movements during mastication and often refractory to standard treatments for dystonia. Emerging evidence suggests that peripheral sensory modulation may play a role in dystonia pathophysiology, but this has not been systematically evaluated as potential treatment modality.
Objectives: The aim of this study was to explore the therapeutic and neurophysiological effects of intraoral topical lidocaine in patients with task-specific chewing dystonia.
Dystonia
August 2025
Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, United States of America.
Dystonia causes involuntary, patterned movements and posturing, often leading to disability, pain, and reduced quality-of-life. Despite standard treatments such as botulinum toxin (BoNT) injections, oral medications, and deep brain stimulation therapy, many patients continue to experience persistent symptoms. There is growing evidence supporting the use of rehabilitation-based therapies in the management of certain forms of dystonia.
View Article and Find Full Text PDFMov Disord
August 2025
Department of Physical Therapy, MGH Institute of Health Professions, Boston, Massachusetts, USA.
Background: The central pathology causing idiopathic focal dystonia remains unclear. The recently identified somato-cognitive action network (SCAN) has been implicated.
Objective: We tested whether the effector-agnostic SCAN may constitute a central pathology shared across dystonia subtypes, whereas the effector-specific regions in the primary sensorimotor cortex may show distinct functional changes specific to the dystonic body part.
Tremor Other Hyperkinet Mov (N Y)
July 2025
Professor of Neurology, NYU Grossman School of Medicine, 222 East 41 Street, 13 floor, New York, NY 10017, US.
Background: Focal task-specific dystonia of the musicians' arm (FTSDma) is an unusual and challenging disorder, often causing significant disability with loss of performing careers. The etiology and optimal management of this disorder remains unclear.
Methods: We reviewed records and videos of 173 patients with FTSDma, 50 patients with writer's cramp (WC), and 16 with other forms of arm dystonia (OD), evaluated by a single examiner in clinical practice over a 25-year period.