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Pits have been observed on many cometary nuclei mapped by spacecraft. It has been argued that cometary pits are a signature of endogenic activity, rather than impact craters such as those on planetary and asteroid surfaces. Impact experiments and models cannot reproduce the shapes of most of the observed cometary pits, and the predicted collision rates imply that few of the pits are related to impacts. Alternative mechanisms like explosive activity have been suggested, but the driving process remains unknown. Here we report that pits on comet 67P/Churyumov-Gerasimenko are active, and probably created by a sinkhole process, possibly accompanied by outbursts. We argue that after formation, pits expand slowly in diameter, owing to sublimation-driven retreat of the walls. Therefore, pits characterize how eroded the surface is: a fresh cometary surface will have a ragged structure with many pits, while an evolved surface will look smoother. The size and spatial distribution of pits imply that large heterogeneities exist in the physical, structural or compositional properties of the first few hundred metres below the current nucleus surface.
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http://dx.doi.org/10.1038/nature14564 | DOI Listing |
Crit Rev Food Sci Nutr
September 2025
Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt.
The olive oil industry generates vast amounts of by-products, including olive pomace, olive mill wastewater, olive pits, and olive leaves, which pose serious environmental and economic challenges. However, these residues are rich in bioactive compounds such as polyphenols, dietary fibers, unsaturated fatty acids, and sugar derivatives, making them valuable resources for sustainable valorization. This review explores innovative biotechnological and probiotic-driven approaches to convert olive waste into high-value products, aligning with the United Nations Sustainable Development Goals (SDGs), particularly SDG 12 (Responsible consumption and production) and SDG 13 (Climate action).
View Article and Find Full Text PDFZhonghua Kou Qiang Yi Xue Za Zhi
September 2025
Department of Prosthodontics I, Stomatological Hospital of Xiamen Medical College & Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment, Xiamen 361008, ChinaLin Jing works at Department of Stomatology, Affiliated Hospital of Putian University, Putian 351100, China.
To investigate the effects of nine polishing protocols on the bonding interface of three types of resin-based ceramic onlays, aiming to identify efficient and reasonable polishing procedures for each type of resin-based ceramic. Forty-six extracted molars were selected and symmetrically sectioned mesiodistally (=92). After preparing 2 mm deep box-shaped cavities on the buccal and lingual surfaces, the samples were randomly divided into four groups (23): LU group (Lava Ultimate), VE group (Vita Enamic), H group (Zirconia-Reinforced Resin-Based Ceramic), and Si group (glass ceramic).
View Article and Find Full Text PDFAm J Hum Genet
August 2025
Department of Human Genetics, Emory University, Atlanta, GA 30322, USA. Electronic address:
Van der Woude syndrome (VWS) is an autosomal dominant disorder characterized by lower lip pits and orofacial clefts (OFCs). With a prevalence of ∼1 in 35,000 live births, it is the most common form of syndromic clefting. Most VWS is attributed to variants in IRF6 (∼70%) or GRHL3 (∼5%), leaving up to 25% of individuals without a molecular diagnosis.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
August 2025
Department of Public Health Dentistry, ACPM Dental College, Dhule, Maharashtra, India.
Background: In modern dentistry, the focus is more on preventing caries than treating them, which helps preserve tooth structure. There is an approximately 50 % prevalence of caries on the occlusal surface in school children. Pits and fissures with irregularities and invasions are responsible for this.
View Article and Find Full Text PDFJ Surg Case Rep
August 2025
Department of Ophthalmology, Loma Linda University, 11370 Anderson St., Suite 1800, Loma Linda, CA 92354, United States.
Optic disc pit maculopathy is a serious complication of congenital optic disc pits, often resulting in significant vision loss due to intraretinal and subretinal fluid accumulation. This case report describes a 35-year-old woman with progressive visual decline in her right eye. Examination revealed optic disc pit maculopathy with marked central foveal thickness (634 μm) and a best-corrected visual acuity of 20/100.
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