Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
There is a growing demand for the rapid determination of hard-to-detect radionuclides in environmental and biological samples for environmental monitoring, radiological protection, and nuclear forensic reasons. A new method using five-column chromatography separation has been developed for the simultaneous determination of Pu, Np, Th, U, Am, Cm, Pm, Y, and Sr isotopes, as well as iron-55, by inductively coupled mass spectrometry (ICPMS), α spectrometry, Čerenkov and liquid scintillation (LS) counting. Spiked swipe and water samples as well as proficient testing water standards were analyzed to validate the separation procedure, and the results are in good agreement with the expected values. The method provides quick sample turnaround time and high analysis throughput with low analysis cost. The flexibility of the method also allows for its easy adaptation to various emergency and routine radioassays.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ac500572g | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pseudomorphic synthesis of pore size-tunable mesoporous silica spherical particles and their application for the fraction of low-molecular-weight heparin.
J Sep Sci
September 2024
Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
In this study, spherical silica with pore size varied from 30 to 200 Å was synthesized by pseudomorphic transformation at atmospheric pressure. 40-80 Å silica particles with a narrow pore distribution were obtained by using quaternary amine cationic surfactants and different kinds of swelling agents, including polypropylene glycol, 1,3,5-trimethylbenzene, alkanes, and alkanols. Alkyl imidazolium ionic liquid surfactants were used to synthesize large pore size distribution silica spheres with pore sizes in the range of 110-200 Å.
View Article and Find Full Text PDFPurification and Identification of the 20S Proteasome Complex from Zebrafish.
Zebrafish
February 2022
Integrated Bioscience Section, Graduate School of Science and Technology, National University Corporation, Shizuoka University, Shizuoka, Japan.
The proteasome is a large polymeric protease complex responsible for degradation of intracellular proteins and generation of peptides. In this study, we purified a native 20S proteasome protein complex from zebrafish () from the whole body. The cytosolic fraction of zebrafish hydrolyzed Suc-Leu-Leu-Val-Tyr-MCA (Suc-LLVY-MCA), a well-known substrate for the proteasome, in the presence of sodium dodecyl sulfate.
View Article and Find Full Text PDFStructural and functional characterization of recombinant human growth hormone isolated from transgenic pig milk.
PLoS One
September 2020
CHO-A Biotechnology Research Institute, CHO-A Pharmaceutical Company, Yeoju-si, Gyeonggi-do, Korea.
Article Synopsis
- The study focused on creating transgenic pigs that produce human growth hormone (hGH) in their milk, aiming to purify and characterize the hormone for potential therapeutic uses.
- The researchers successfully extracted highly pure hGH from ~15.5 L of pig milk and confirmed its similarity to a commercial product, Genotropin, through various analyses.
- Additionally, experiments on rats demonstrated that the milk-derived hGH (CGH942) promotes growth without any observed toxic effects, indicating a promising new method for producing human therapeutic proteins.
Determination of pesticides in fatty matrices using gel permeation clean-up followed by GC-MS/MS and LC-MS/MS analysis: A comparison of low- and high-pressure gel permeation columns.
Talanta
April 2017
Nestlé Research Centre, Vers-Chez-les-Blanc, PO Box 44, CH-1000 Lausanne 26, Switzerland. Electronic address:
Two low-pressure columns (Bio-Beads SX-3) and three high-pressure GPC columns were compared for clean-up of a wide range of pesticides in fatty matrices of vegetable or animal origin. The GPC fractions were analyzed by GC-MS/MS and LC-MS/MS without additional clean-up. The performance of the GPC clean-up on the five column types was compared in terms of solvent consumption, lipid removal, pesticide recovery and repeatability.
View Article and Find Full Text PDFEnantioseparation of racemic aminoglutethimide using asynchronous simulated moving bed chromatography.
J Chromatogr A
October 2016
Laboratory of Separation and Reaction Engineering (LSRE), Associate Laboratory LSRE/LCM, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal.
The separation of aminoglutethimide enantiomers by the continuous multicolumn chromatographic processes were investigated experimentally and theoretically, where the columns were packed with cellulose tris 3,5-dimethylphenyl-carbamate stationary phase (brand name Chiralcel OD) and mobile phase was a mixture of n-hexane and ethanol with monoethanolamine additive. The continuous enantioseparation processes included a synchronous shifting process (SMB) and an asynchronous shifting process (VARICOL), which allowed reducing the column number (here from six-column SMB to five-column VARICOL process). Transport-dispersive model with the consideration of both intraparticle mass transfer resistance and axial dispersion was adopted to design and optimize the operation conditions for the separation of aminoglutethimide enantiomers by SMB process and VARICOL process.
View Article and Find Full Text PDF