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Article Abstract
Whether M cells arise from a distinct lineage or result from phenotypic transition is a matter of debate. In this issue of Cell Host & Microbe, Tahoun et al. (2012) provide evidence that SopB, a virulence factor of Salmonella enterica serovar Typhimurium, can induce phenotypic transition of lymphoid follicle-associated enterocytes into M cells.
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