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Herein, we report the synthesis of three covalently linked superparamagnetic nanocrystal-multi-walled carbon nanotube (MWCNT) composites. A generic strategy for amphiphilic polymer coating of nanocrystals and further functionalization for amide bond formation with the MWCNTs is discussed. This approach can in principle allow attachment of any colloidal nanocrystal to the MWCNTs. The materials were characterized at each stage of the syntheses using DLS, zeta-potential measurements, FT-IR, TEM, and XPS techniques. The practicality of this linkage is demonstrated by the reversible magnetic immobilization of these materials on an electrode during non-aqueous electrochemistry.
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http://dx.doi.org/10.1016/j.jcis.2012.06.028 | DOI Listing |
Int J Toxicol
September 2025
Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.
Polyethylene glycols (PEGs) are amphiphilic polymers that are used extensively in consumer products and PEGylated biotherapeutics. Although PEGs are considered biologically inert with a low toxicity, anti-PEG antibodies have been detected in patients receiving treatment with PEGylated biotherapeutics as well as in healthy individuals. Despite continual exposure in daily life, the prevalence of PEGs within the general population remains unclear.
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September 2025
Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Universitätsstr. 1, 40225 Düsseldorf, Germany; Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich, Germany; Jülich Ce
Many membrane proteins, including G protein-coupled receptors (GPCRs), are susceptible to denaturation when extracted from their native membrane by detergents. Therefore, alternative methods have been developed, including amphiphilic copolymers that enable the direct extraction of functional membrane proteins along with their surrounding lipids. Among these amphiphilic copolymers, styrene/maleic acid (SMA) and diisobutylene/maleic acid (DIBMA) polymers have been extensively studied.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address:
Sulforaphene (SFE) is a bioactive isothiocyanate, known for its cancer-preventive, anti-inflammatory, and antioxidant properties. However, the application of SFE is severely limited by its poor stability. Hydroxypropyl methylcellulose (HPMC), an amphiphilic carbohydrate polymer, has potentials to enhance the stability of SFE and the loading capacity.
View Article and Find Full Text PDFChempluschem
September 2025
Provincial Engineering Research Center for Biomedical Materials and Advanced Medical Devices, Huaiyin Institute of Technology, Huai'an, Jiangsu, 223003, China.
Enhancing singlet oxygen generation for photosensitizers in aqueous media can markedly improve the efficacy of photochemical therapy. Herein, triblock polymers composed of pyropheophorbide a photosensitizer (PPa), polyethylene glycol, and phospholipid are synthesized. These triblock polymers, driven by hydrophilic-hydrophobic interactions, spontaneously fold into an amphiphilic structure and further self-assemble into nanomicelles.
View Article and Find Full Text PDFJ Photochem Photobiol B
August 2025
College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal Un
Mild photothermal therapy effectively reduces hyperthermia-related tissue injuries; however, its low therapeutic efficiency presents a significant limitation. Herein, we developed an organic multifunctional photothermal platform with enhanced Fenton catalytic activity to increase tumor sensitivity to mild photothermal therapy. This platform incorporated a self-augmented Fenton molecule integrating carbonic anhydrase inhibitor and ferrocene, which was co-encapsulated with the photothermal agent IR 825 via an amphiphilic polymer.
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